Generex Subsidiary NuGenerex Immuno-Oncology Announces World Class Scientific Advisory Board Appointments for its COVID-19 Vaccine Development Program - Seite 3

Generex CEO, Joseph Moscato said, “I would like to thank these distinguished and highly respected physician researchers, all from prestigious institutions, for joining us in our efforts to create a safe and effective vaccine against COVID-19 that can be used not only in adults, but also in pediatric populations who have so far been excluded from the vaccine discussion. Our Ii-Key vaccine is designed as a “Complete Vaccine”, which can generate neutralizing antibodies via the humoral immune response and can activate the CD4+ and CD8+ cellular responses in a safe manner to avoid the complications of off target immune effects that lead to the cytokine storm and autoimmune diseases. As all of our Ii-Key vaccines are peptide-based and targeted to specific regions of the coronavirus rather than gene therapy based and including the entire spike protein of the virus, and since we have demonstrated the safety of our other Ii-Key vaccines in Phase IIb human clinical trials, we believe that our technology offers the safest and best route for the rapid development of a pediatric Ii-Key-SARS-CoV-2 vaccine. Of course, we plan to move forward with the first in human studies of the vaccine in healthy adults, however, because of the clean safety profiles of our other Ii-Key vaccines, we hope to conduct clinical trials in adolescents, children, and pregnant women on a safe and expedited path to address this glaring unmet need in our fight against this COVID-19 pandemic. We look forward to working closely with our SAB as we move the Ii-Key-SARS-CoV-2 vaccine through the global regulatory process.”

About Generex Biotechnology Corp.
Generex Biotechnology is an integrated healthcare holding company with end-to-end solutions for patient centric care from rapid diagnosis through delivery of personalized therapies. Generex is building a new kind of healthcare company that extends beyond traditional models providing support to physicians in an MSO network, and ongoing relationships with patients to improve the patient experience and access to optimal care.

About NuGenerex Immuno-Oncology
NuGenerex Immuno-Oncology, a subsidiary of Generex Biotechnology, is a clinical stage oncology company developing immunotherapeutic peptide vaccines for cancer and infectious disease based on the CD4 T-Cell activation platform, Ii-Key. NuGenerex Immuno-Oncology (NGIO) has been spun out of Generex as a separate public company to advance the platform Ii-Key technology, particularly in combination with the immune checkpoint inhibitors for the treatment of cancer. NGIO is currently engaged in a Phase II clinical trial of its lead cancer immunotherapeutic vaccine AE37 in combination with pembrolizumab (Merck’s Keytruda) for the treatment of triple negative breast cancer. The company has also turned its Ii-Key technology on infectious disease, responding to the coronavirus pandemic with a SARS-CoV-2 vaccine development program.