Transparency Notification

THIS ANNOUNCEMENT CONTAINS REGULATED INFORMATION.

PUBLICATION RELATING TO A TRANSPARENCY NOTIFICATION (ARTICLE 14, 1ST PARAGRAPH, OF THE LAW OF 2 MAY 2007 ON THE DISCLOSURE OF MAJOR HOLDINGS)

Acacia Pharma Group plc

 1.     Summary of the notification

Cambridge, UK and Indianapolis, US – 26 February 2021, 08:00 CET: Acacia Pharma Group plc has received a transparency notification dated 23 February 2021 indicating that Cosmo Pharmaceuticals N.V now holds, by virtue of the issue of shares on 23 February 2021, 19.66% of the voting rights of the company. Cosmo has therefore crossed the threshold of 20%.

2.     Content of notification
The notification dated 23 February 2021 contains the following information:

• Reason of the notification – passive crossing of a threshold
• Notification by – a parent undertaking or a controlling person
• Persons subject to the notification requirement – Cosmo Pharmaceuticals N.V. Riverside 2, Sir John Rogerson’s Quay, Dublin 2, Ireland
• Date on which the threshold is crossed – 23 February 2021
• Threshold that is crossed – 20%
• Denominator – 99,689,451
• Notified details:

A)     Voting rights	Previous notification	After the transaction
	# of voting rights	# of voting rights		% of voting rights
Holders of voting rights		Linked to securities	Not linked to securities	Linked to securities	Not linked to securities
Cosmo Pharmaceuticals N.V.	0	0	0	0.00%	0.00%
Cosmo Technologies Ltd.	19,600,098	19,600,098	0	19.66%	0.00%
Subtotal	19,600,098	19,600,098		19.66%
	TOTAL	19,600,098	0	19.66%	0.00%