Revolutionizing Vaccine Discovery

New Data Validates Evaxion AI Platform, Offering Promise to Reduce Risk and Cost in Infectious Disease Vaccine Development

• Evaxion is the first organization to validate an AI model that outcompetes state-of-the-art vaccine development
• Evaxion's AI model predicts vaccine efficacy in infectious disease models
• These results mean using EDEN^TM will allow for a faster, cheaper, and lower-risk vaccine development compared to current approaches

COPENHAGEN, Denmark, Sept. 11, 2023 (GLOBE NEWSWIRE) -- Evaxion Biotech A/S (NASDAQ: EVAX) ("Evaxion" or the "Company"), a clinical-stage biotechnology company specializing in the development of AI-powered immunotherapies, has achieved a groundbreaking milestone in vaccine discovery with the validation of its AI-powered vaccine discovery platform, EDEN^TM. Data will be shared at the Vaccines Europe conference in Berlin, Germany, taking place from September 14th to 15th.

Evaxion's newly appointed CEO, Christian Kanstrup, commented, "These exciting results highlight the unique ability of our AI platforms to quickly generate novel targets. This acceleration in vaccine development not only reduces costs but also minimizes risks, particularly impacting areas with high unmet medical needs lacking existing vaccines. We are truly excited about this opportunity to make a significant difference in the fight against the growing challenge of bacterial diseases. I look forward to discussing these groundbreaking findings with potential partners."

"We are thrilled to present clear evidence validating EDEN^TM's ability to select immunologically relevant vaccine targets in a completely automated and unbiased fashion. Through proteome-wide AI predictions, this tool not only identifies protective proteins but also predicts the protection level each offers," remarked Founder and Chief AI Officer Andreas Holm Mattsson.

Andreas Holm Mattsson concluded, "Evaxion thus becomes the first organization to identify and design bacterial vaccine antigens solely through computational methods, outcompeting reverse vaccinology approaches. We believe this heralds a paradigm shift in vaccine discovery."

The talk titled "Novel AI-Powered Vaccine Target Discovery Platforms for Bacterial & Viral Infectious Diseases" will be featured at Vaccines Europe 2023, showcasing compelling data affirming EDEN^TM capabilities through multiple bacterial pathogens and preclinical infection models. Notably, the antigens predicted by EDEN^TM to offer the highest level of protection are those found to perform best in preclinical infection models, confirming their potential as vaccine components. This correlation between AI prediction and in vivo protection has been established for multiple bacterial pathogens for which human vaccines are currently unavailable.