14 Studies Presented at AUA 2024 Show Decipher Tests’ Ability to Help Personalize Care for Prostate and Bladder Cancer Patients and Advance Disease Understanding

Veracyte, Inc. (Nasdaq: VCYT), a leading cancer diagnostics company, today announced that data from 14 presentations at AUA 2024, the annual meeting of the American Urological Association, show that the Decipher Prostate and Decipher Bladder Genomic Classifiers provide better prognostic information for patients with prostate and bladder cancer, compared to standard approaches. They also show that the research-use-only Decipher GRID (Genomic Resource for Intelligent Discovery) tool is helping to advance scientific understanding of these diseases. The findings were presented during the conference taking place May 3-6 in San Antonio.

“The large amount of data presented at AUA 2024 reinforces Veracyte’s commitment to building rigorous evidence that demonstrates our tests’ performance and clinical utility,” said Elai Davicioni, Ph.D., Veracyte’s medical director for Urology. “Further, our whole-transcriptome approach to testing provides an incredible amount of data that we are pleased to share with the research community through Decipher GRID to help advance understanding of urologic cancers and ultimately improve patient outcomes.”

Studies showing the Decipher Prostate test’s ability to better inform prostate cancer treatment include:

• Poster MP41-09: Genomic Signatures Associated with Adverse Pathologic Features at Radical Prostatectomy Among Active Surveillance Eligible Men. Presented by Eric Li, M.D., Northwestern University.
  
  Summary: The Decipher Prostate Genomic Classifier is associated with adverse pathology in patients eligible for Active Surveillance (AS) who were treated with radical prostatectomy (RP). The findings suggest the Decipher test may be able to identify patients at increased risk of harboring higher grade and non-organ confined disease who may not be ideal candidates for AS.
  
  “Despite having similar clinical features at diagnosis, our study suggests that AS-eligible prostate cancer patients have a spectrum of risk for occult adverse pathology that can be elucidated at the level of gene expression," said Ashley Ross, M.D., Ph.D., clinical director for the Polsky Urological Oncology Center at Northwestern University and principal investigator on the study. “Our results suggest that use of the Decipher Prostate test may help clinicians better stratify risk among patients eligible for AS, which may ultimately help reduce under- and over-treatment.”