2018 Iron Deficiency Day

A Call to Develop a Better Understanding of Iron Deficiency - Seite 3

Iron deficiency is very common present in one-third of people around the world.² It is most prevalent in premenopausal and pregnant women and children under the age of five.³ In Europe for example, iron deficiency affects up to 33% of pre-menopausal women, up to 77% of pregnant women, and up to 48% of children³. Iron deficiency is also frequently associated with chronic inflammatory diseases such as chronic heart failure, chronic kidney disease and irritable bowel disease.⁴

Iron is required throughout the body. It is essential for the production of red blood cells, and ensuring that the heart and skeletal muscles can function effectively.¹⁵ Iron also plays a vital role in fighting off infections and illness,¹⁶ maintaining energy levels¹⁶ and normal brain function.¹⁷ When the body’s available iron stores are low (iron deficiency) it can impact almost all aspects of life such as metabolism, mental and physical health, work productivity and even sexual function.^{5, 17} The World Health Organization states that iron deficiency can lead to a reduction of 30% in physical work output.¹⁸

For more information visit www.irondeficiencyday.com.

References

1. Hassan, Tamer Hasan et al. “Impact of Iron Deficiency Anemia on the Function of the Immune System in Children.” Ed. Esaki M. Shankar. Medicine 95.47 (2016): e5395. PMC. Web. 12 June 2018.
2. Peyrin-Biroulet L, et al. Guidelines on the diagnosis and treatment of iron deficiency across indications: a systematic review. Am J Clin Nutr. 2015;102(6):1585-94.
3. Hercberg S, et al. Iron deficiency in Europe. Public Health Nutr. 2007;4(2b).
4. Cappellini MD et al. Iron deficiency across chronic inflammatory conditions: International expert opinion on definition, diagnosis, and management. Am J Hematol. 2017 Oct;92(10):1068-1078.
5. Auerbach M, Adamson JW. How we diagnose and treat iron deficiency anemia. Am J Hematol. 2016;91(1):31-38.
6. Thachil J. Iron deficiency: still under-diagnosed? Br J Hosp Med. 2015;76(9):528-532.
7. Miller JL. Anemia: a common and curable disease. Cold Spring Harb Perspect Med. 2013 Jul; 3(7).
8. Caramelo L, Mezzacasa A and Kassebaum NJ. Iron Deficiency. Understanding perceptions of sufferers and the general public. EHA 21st Annual Congress, 9-12 June 2016, Copenhagen, Denmark.
9. Fernando B, et al. A guide to diagnosis of iron deficiency and iron deficiency anemia in digestive diseases. World J Gastroenterol. 2009 Oct 7; 15(37): 4638-4643.
10. Favrat, B., et al. (2014). Evaluation of a single dose of ferric carboxymaltose in fatigued, iron-deficient women--PREFER a randomized, placebo-controlled study. PLoS One 9(4): e94217. eCollection 2014. <
11. Cashman MW, Sloan SB. Nutrition and nail disease. Clin Dermatol. 2010;28(4):420-5.
12. Barton JC, et al. Pica associated with iron deficiency or depletion: clinical and laboratory correlates in 262 non-pregnant adult outpatients. BMC Blood Disord. 2010;10:9. doi:10.1186/1471-2326-10-9.
13. Patterson A et al. Iron deficiency, general health and fatigue: Results from the Australian Longitudinal Study on Women’s Health. Qual Life Res. 2000;9:491-497.
14. World Health Organisation. Nutritional anaemias: tools for effective prevention and control. 2017. Available at URL: http://www.who.int/nutrition/publications/micronutrients/anaemias-tool .... Last accessed: June 2018.
15. Camaschella C. 2015. Iron‐deficiency anemia. N. Engl. J. Med. 372:1832–1843.
16. Beard JL. Iron biology in immune function, muscle metabolism and neuronal functioning. J Nutr. 2001:568-580.
17. Pinero DJ, Connor JR. Iron in the Brain: An Important Contributor in Normal and Diseased States. Neurosci. 2000;6(6):435-453.
18. World Health Organisation. Iron deficiency anaemia. Assessment, prevention and control: A guide for programme managers. 2001. Available at URL: http://www.who.int/nutrition/publications/en/ida_assessment_prevention ... Last accessed: June 2018.