Paroxysmal Nocturnal Hemoglobinuria Market Landscape Set to Witness Growth at a CAGR of 10% for the Study Period 2018-30 in the 7MM | DelveInsight - Seite 2

The Paroxysmal Nocturnal Hemoglobinuria market report offers available therapies, treatment landscape, emerging therapies, changing market landscape, individual market share of pipeline therapies, PNH market drivers, and market barriers, PNH market size during the study period 2018-30 in the 7MM (the US, EU5 (the UK, Germany, Italy, Spain and France), and Japan).

Paroxysmal Nocturnal Hemoglobinuria is a rare acquired disorder of the pluripotent hematopoietic stem cell; therefore, it can affect erythrocytes, leukocytes, thrombocytes, and probably some endothelial cells. Paroxysmal Nocturnal Hemoglobinuria diagnosis is made based on clinical evaluation, patient history, and several tests that are specialized to identify Paroxysmal Nocturnal Hemoglobinuria cells such as flow cytometry. 

Paroxysmal Nocturnal Hemoglobinuria symptoms often include fatigue, difficulty in swallowing (dysphagia), shortness of breath (dyspnea), pain in the abdomen, anemia, erectile dysfunction, and dark-colored urine (hemoglobinuria). However, hemolysis in Paroxysmal Nocturnal Hemoglobinuria that leads to thrombosis remains to be the most devastating consequence of the blood disorder and can often prove to be fatal. 

 Paroxysmal Nocturnal Hemoglobinuria Epidemiological Analysis & Forecast

Paroxysmal Nocturnal Hemoglobinuria is an ultra-rare blood disorder, and DelveInsight's 7MM Paroxysmal Nocturnal Hemoglobinuria epidemiological analysis demonstrates that it is primarily more common in females than males. Further, the US accounted for the highest diagnosed prevalent cases, approximately 51% of the total cases in the 7MM, followed by Germany. 

The PNH market analysis report proffers historical as well as forecasted epidemiological segmentation for the study period 2018-30: 

• Total diagnosed Paroxysmal Nocturnal Hemoglobinuria prevalent cases 
• Gender-specific Paroxysmal Nocturnal Hemoglobinuria cases 

Dive deeper for rich insights into Paroxysmal Nocturnal Hemoglobinuria Epidemiological Analysis 

Paroxysmal Nocturnal Hemoglobinuria Treatment Landscape 

Before the approval of anti-C5 agent-Eculizumab, Paroxysmal Nocturnal Hemoglobinuria was a devastating disease that would lead to breaking of red blood cells prematurely. However, Eculizumab transformed the Paroxysmal Nocturnal Hemoglobinuria treatment landscape. The therapeutic agent not only helped in the management of hemolysis, but also helped in reducing the rate of thrombosis and the number of transfusions. It managed to push bone marrow transplantation to second-line therapy for hemolytic PNH in countries where the drug is available.