EQS-Adhoc

Relief Therapeutics' Wholly Owned Subsidiary, APR Applied Pharma Research, Receives Notice of Allowance of Key U.S. Patent Application Covering Ready to Use Diclofenac Stick Packs - Seite 2

The USPTO issues a patent Notice of Allowance after it determines a patent should be granted upon completion of any outstanding administrative requirements. The allowed claims are for a (i) single dose, ready to use oral solutions provided as liquid formulations in a stick pack containing diclofenac or a salt thereof, and (ii) methods of treating pain or migraine in a patient in need thereof comprising administering to said patient a therapeutically effective amount of the various diclofenac formulations. Once issued, the patent will have an expiration date of December 13, 2039.

"The receipt of this Notice of Allowance from the USPTO is another confirmation of our drug development and reformulation expertise," stated Paolo Galfetti, Chief Executive Officer of APR and President of Relief Europe. "The new, user friendly, ready to use, liquid portable stick packs to deliver CAMBIA should improve patient compliance. We look forward to continue to identify, develop and commercialize innovative therapies for patients with niche and rare diseases."

ABOUT RELIEF

Relief focuses primarily on clinical-stage programs based on molecules with a history of clinical testing and use in human patients or a strong scientific rationale. Relief's lead drug candidate, RLF-100(TM) (aviptadil), a synthetic form of Vasoactive Intestinal Peptide (VIP), is in late-stage clinical testing in the U.S. for the treatment of respiratory deficiency due to COVID-19 through Relief's collaboration partner in the U.S., NeuroRx, Inc. As part of its pipeline diversification strategy, in March 2021, Relief entered into a Collaboration and License Agreement with Acer Therapeutics for the worldwide development and commercialization of ACER-001. ACER-001 is a taste-masked and immediate release proprietary powder formulation of sodium phenylbutyrate (NaPB) for the treatment of Urea Cycle Disorders and Maple Syrup Urine Disease. Finally, Relief's recently completed acquisitions of APR Applied Pharma Research SA and AdVita Lifescience GmbH, bring to Relief a diverse pipeline of marketed and development-stage programs.