Twist Bioscience Launches IVDR-compliant Precision Dx Products for Whole Exome Sequencing - Seite 2

The Precision Dx workflow enables comprehensive coverage with more than 98% of target bases covered at 30x as well as reliable performance with uniform enrichment and consistent yield from high-complexity libraries. The Precision Dx Products are intended for use with high-quality genomic DNA derived from human cells and allow for flexibility within workflows.

Twist Precision Prep and Enrichment Dx Kit

The Twist Precision Prep and Enrichment Dx Kit¹ is a reagent kit that includes enzymatic fragmentation, library preparation, and targeted capture. It utilizes Twist’s expertise in enzymatic DNA fragmentation and library preparation to enable reliable access to target DNA for NGS. The kit’s streamlined workflow combines library preparation steps into a single-tube reaction which, alongside a high on-target rate and Twist’s highly uniform target enrichment workflow, translates into an enhanced quality library preparation and sequencing result. The kit can be used to target specific regions of the genome with DNA panels supplied by users or with a Twist DNA panel, such as the Twist Precision Exome Dx Panel, for NGS applications.

Twist Precision Exome Dx Panel

The Twist Precision Exome Dx Panel¹ is a qualified Twist DNA panel that can be used in conjunction with the Twist Precision Prep and Enrichment Dx kit to produce exome-enriched libraries compatible for NGS applications. The panel expands exonic coverage to include the mitochondrial genome as well as additional clinically relevant loci, providing efficient and comprehensive exome sequencing for improved coverage of target sequences.

Twist Precision Exome Dx Kit

Twist Precision Exome Dx Kit¹ utilizes the qualified Twist Precision Exome Dx Panel along with the Twist Precision Prep and Enrichment Dx Kit to produce exome-enriched libraries compatible for NGS applications.

1		For in vitro diagnostic use. Not available in all regions and countries.
2		Panels supplied by users must meet Twist specifications, available upon request.

About Twist Bioscience Corporation

Twist Bioscience is a leading and rapidly growing synthetic biology and genomics company that has developed a disruptive DNA synthesis platform to industrialize the engineering of biology. The core of the platform is a proprietary technology that pioneers a new method of manufacturing synthetic DNA by “writing” DNA on a silicon chip. Twist is leveraging its unique technology to manufacture a broad range of synthetic DNA-based products, including synthetic genes, tools for next-generation sequencing (NGS) preparation, and antibody libraries for drug discovery and development. Twist is also pursuing longer-term opportunities in digital data storage in DNA and biologics drug discovery. Twist makes products for use across many industries including healthcare, industrial chemicals, agriculture and academic research.