Poolbeg Pharma PLC Announces Results for the Year Ended 31 December 2023 - Seite 2

• Positive in vivo data confirmed POLB 001's efficacy in reducing cancer immunotherapy-induced CRS in an animal model, strengthening and facilitating the expansion of patent applications for POLB 001 in cancer immunotherapy-induced CRS
• Independent Advisory Board of Key Opinion Leaders, healthcare payers and clinical trial experts, were supportive of POLB 001's potential to both prevent and treat cancer immunotherapy-induced CRS
• Independent research confirmed a market opportunity exceeding US$10 billion^[1] for POLB 001 as an orally delivered preventative therapy for cancer immunotherapy-induced CRS
• Cathal Friel, Co-Founder and significant shareholder, assumed the role of Executive Chairman

Jeremy Skillington, PhD, Chief Executive Officer of Poolbeg Pharma, commented: "We made excellent progress and hit multiple key milestones in 2023, the most important of all perhaps was filing patent applications which will give us international protection over the use of POLB 001 as a preventative therapy for cancer immunotherapy-induced CRS, in addition to the existing severe influenza indication. With a market opportunity exceeding US$10 billion in cancer immunotherapy-induced CRS, positive data generated, and a robust patent portfolio - POLB 001 has great potential to generate significant value for shareholders.

"Our disciplined approach to capital allocation has ensured that we have maintained a robust cash position. We remain focussed and are getting good engagement on partnering to maximise the value of our in-house programmes. Poolbeg has the expertise to succeed in our strategy of developing, partnering and commercialising innovative medicines to generate near-term revenues with a goal to achieve sustainable profitability.

"Going forward, I believe we are well positioned to generate value for our shareholders, while addressing significant unmet medical needs across multiple disease areas."

Investor presentation

Poolbeg's management team will provide a live presentation via the Investor Meet Company platform on Tuesday 30 April 2024 at 6pm BST.

The presentation is open to analysts and investors, those who already follow Poolbeg on the Investor Meet Company platform will automatically be invited. Investors can sign up to Investor Meet for free and add Poolbeg Pharma plc to their company dashboard here.