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     2614  0 Kommentare ABLYNX INITIATES PHASE I BIOAVAILABILITY STUDY WITH SUBCUTANEOUS FORMULATION OF ITS ANTI-IL-6R NANOBODY PARTNERED WITH ABBVIE - Seite 2

    About RA and SLE

    RA is characterised by chronic and progressive joint inflammation that typically results in permanent, debilitating tissue damage, which is further compounded by joint deformation. The condition is associated with lower quality of life, premature death, disability, and unemployment. It is estimated that up to 1 percent of the adult population worldwide suffer from RA.

    SLE is a complex, multi-organ, autoimmune disorder characterised by the production of pathogenic autoantibodies and tissue deposition of immune complexes, which result in widespread tissue damage. Although the etiology of SLE is not fully understood, multiple genetic, environmental, and hormonal factors have been implicated in its development. The disease displays a broad variety of symptoms and highly variable clinical features, including systemic, cutaneous, renal, musculoskeletal, and haematological manifestations. Approximately 5 million people worldwide suffer from a form of lupus and 90 percent of people diagnosed are women.

    About Ablynx

    Ablynx is a biopharmaceutical company engaged in the discovery and development of Nanobodies®, a novel class of therapeutic proteins based on single-domain antibody fragments, for a range of serious human diseases, including inflammation, haematology, oncology and pulmonary disease. Today, the Company has approximately 30 programmes in the pipeline and seven Nanobodies in clinical development. Ablynx has on-going research collaborations and significant partnerships with major pharmaceutical companies including AbbVie, Boehringer Ingelheim, Eddingpharm, Merck & Co, Merck Serono and Novartis. The Company is headquartered in Ghent, Belgium.

    More information can be found on www.ablynx.com.

    For more information, please contact

    Ablynx:

    Dr Edwin Moses
    CEO
    t:   +32 (0)9 262 00 07
    m: +44 (0)7771 954 193 /
         +32 (0)473 39 50 68
    e:  edwin.moses@ablynx.com

    Marieke Vermeersch
    Associate Director Investor Relations
    t:   +32 (0)9 262 00 82
    m: +32 (0)479 49 06 03
    e:  marieke.vermeersch@ablynx.com
    Follow us on Twitter @AblynxABLX

    Ablynx media relations Consilium Strategic Communications:

    Mary-Jane Elliott, Amber Bielecka, Lindsey Neville
    t:   +44 203 709 5700
    e:  ablynx@consilium-comms.com





    This announcement is distributed by NASDAQ OMX Corporate Solutions on behalf of NASDAQ OMX Corporate Solutions clients.
    The issuer of this announcement warrants that they are solely responsible for the content, accuracy and originality of the information contained therein.
    Source: Ablynx via Globenewswire

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    ABLYNX INITIATES PHASE I BIOAVAILABILITY STUDY WITH SUBCUTANEOUS FORMULATION OF ITS ANTI-IL-6R NANOBODY PARTNERED WITH ABBVIE - Seite 2 GHENT, Belgium, 23 April 2014 - Ablynx [Euronext Brussels: ABLX] today announced that it has started dose administration in healthy volunteers in a Phase I clinical trial as part of the evaluation of a subcutaneous formulation of its anti-IL-6R …