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     753  0 Kommentare AOP Orphan announces three-year results on Ropeginterferon alfa-2b in Polycythemia Vera at ASH - Seite 3

    Ropeginterferon alfa-2b was discovered by PharmaEssentia, a long-term partner of AOP Orphan. Ropeginterferon alfa-2b has Orphan Drug designation in the European Union, Switzerland and the United States of America.

    In 2009, AOP Orphan has in-licensed from PharmaEssentia Corporation the exclusive rights to develop and commercialize Ropeginterferon alfa-2b in PV, other MPNs and CML for European, Commonwealth of Independent States (CIS), and Middle Eastern markets.

    About Polycythemia Vera
    Polycythemia Vera (PV) is a cancer of the blood-building cells in the bone marrow resulting in a chronic increase of red blood cells, white blood cells and platelets. This condition may result in circulatory disorders such as thrombosis and embolism, as well as malignant transformation to myelofibrosis or leukemia. While the molecular mechanism underlying PV is still subject of intense research, current results point to a set of acquired mutations, the most important being a mutant form of JAK2 that make the malignant clone.

    About AOP Orphan Pharmaceuticals AG
    AOP Orphan is a multinational company with headquarters in Vienna, Austria focusing on clinical research, development and distribution of medicines for rare and complex diseases. The company also provides individualized and customized services to meet and accommodate the needs of physicians and patients across Europe, the Middle East & Asia. Currently AOP Orphan is concentrating on rare and complex diseases in HematoOncology, Cardiology & Pulmonology, and Neurology & Metabolic Disorders.

    Contact
    AOP Orphan Pharmaceuticals AG
    Wilhelminenstrasse 91/IIf, 1160 Vienna, Austria
    Dr. Christoph Klade, Chief Scientific Officer
    E: christoph.klade@aoporphan.com

    (Ende)

    Aussender: AOP Orphan Pharmaceuticals Aktiengesellschaft
    Ansprechpartner: AOP
    Tel.: +43 503 72 44-24
    E-Mail: olena.weissenbacher@aoporphan.com
    Website: www.aoporphan.at

    [ Quelle: http://www.pressetext.com/news/20181203045 ]

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    AOP Orphan announces three-year results on Ropeginterferon alfa-2b in Polycythemia Vera at ASH - Seite 3 * High rates of durable hematological response and symptom control with good tolerability were reconfirmed with Ropeginterferon alfa-2b after 36 months of treatment. * Disease Modification by Ropeginterferon alfa-2b was illustrated …