Medical Properties Trust Announces Public Offering of 45,000,000 Shares of Common Stock

Medical Properties Trust, Inc. (the “Company”) (NYSE: MPW) announced today that it has commenced an underwritten public offering to sell 45,000,000 shares of its common stock. The Company intends to grant the underwriters in the offering a 30-day option to purchase up to an additional 6,750,000 shares of its common stock.

The Company intends to use the net proceeds from the offering to partially fund its previously announced acquisitions of a portfolio of 14 acute care hospitals and two behavioral health facilities from Prospect Medical Holdings, Inc. (“Prospect”), and one acute care hospital from Halsen Healthcare (“Halsen”). The offering is not conditioned upon the successful completion of the Prospect or Halsen acquisitions. The Company intends to use any remaining balance of the net proceeds from the offering (or if the Prospect or Halsen acquisitions are not completed) for general corporate purposes, which may include repaying indebtedness (including amounts outstanding from time to time under its revolving credit facility and/or term loan facilities), working capital and capital expenditures, and potential future acquisitions.

Barclays, BofA Merrill Lynch and J.P. Morgan will act as joint book running managers for the offering. The offering will be made under the Company’s effective shelf registration statement previously filed with the Securities and Exchange Commission (the “SEC”). When available, a copy of the preliminary prospectus supplement, final prospectus supplement and the prospectus relating to the offering may be obtained from Barclays Capital Inc., c/o Broadridge Financial Solutions, 1155 Long Island Avenue, Edgewood, NY 11717, by phone at [phone] or by email at [e-mail], from BofA Securities, Inc., NC1-004-03-43, 200 North College Street, 3rd floor, Charlotte NC 28255-0001, Attn: Prospectus Department or by email at [e-mail], from J.P. Morgan Securities LLC, c/o Broadridge Financial Solutions, 1155 Long Island Avenue, Edgewood, NY 11717, or by phone at [phone], or by visiting the EDGAR database on the SEC’s web site at www.sec.gov.

This press release does not constitute an offer to sell or a solicitation of an offer to buy any shares of the Company’s common stock, nor shall there be any sale of these securities in any jurisdiction in which such an offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such jurisdiction.