BioSenic receives a Chinese patent with broad claims, protecting the combined use of metal ions and arsenic salts to treat a wide range of serious diseases

INSIDE INFORMATION

• Composition-of-matter patent covers the therapeutic use of arsenic salts and metal ions through various routes of administration
• Enriched IP portfolio protects ATO with demonstrated therapeutic potential for indications ranging from cancer to immune or infectious diseases

Mont-Saint-Guibert, Belgium, 24 August, 2023, 7.00am CET – BioSenic (Euronext Brussels and Paris: BIOS), the clinical-stage company specializing in serious autoimmune and inflammatory diseases and cell therapy, today announces the issuance of a key new patent entitled ‘Use of metal ions to potentiate the therapeutic effects of arsenic’ to its subsidiary company Medsenic by the China National Intellectual Property Administration (CNIPA). This patent (ZL202080040613.1) covers the use of its ATO platform in combination with metal ions like copper, which has the potential to improve the treatment of autoimmune diseases. The European Patent Office (EPO) granted similar protection (EP3972613) in April 2023.

BioSenic is exploring the therapeutic use of ATO for a number of disease areas, and has recently published peer-reviewed data from several preclinical studies elucidating its mechanisms for modulating immune responses, and the ability of certain metal ions to enhance this therapeutic potential. The intellectual property rights recently secured in EU and China pave the way for clinical and commercial developments by BioSenic and interested partners, particularly in the fields of cancer and autoimmunity.

The patent involves two main immediate areas of application. The first is in immune and autoimmune related diseases such as chronic Graft-versus-Host Diseases (cGvHD), systemic sclerosis and systemic lupus erythematosus. The second is in oncology, where ATO has already demonstrated exceptional results for patients, including complete remission of acute promyelocytic leukaemia. This patent issued by CNIPA is in line with the company’s general strategy of setting a dense and meaningful intellectual property portfolio. Indeed, these patents will support the BioSenic’s plans for international clinical trials in pathologies with unmet medical needs, and toward the company’s long-term goal of seeking market access approvals for its various formulations including the original properties of arsenic salts.