Bionano Genomics Solidifies its Entry into Solid Tumor Analysis with Launch of New Kit and Protocol that Significantly Simplify Tissue and Solid Tumor Analysis - Seite 2
Brandon LaBarge, MD, from the Penn State College of Medicine, who was part of the multisite early access to the new DNA isolation method, commented: “Earlier methods to purify long DNA involved agarose plugs and a tedious protocol with manual washing and digesting steps, taking up to three days to run four samples. These older methods provided inconsistent results, with several tumor samples failing altogether or generating limited throughput. With the new Bionano Prep SP Tissue and Tumor Kit, we were able to isolate ultra-high molecular weight DNA in less than six hours on six samples at a time, generating a consistent, high throughput on a variety of head and neck cancers.”
Mark Oldakowski, Bionano’s Chief Operating Officer commented: “With the launch of the Bionano Prep SP Tissue and Tumor Kit, we are bringing the speed, ease of use and DNA quality of our extremely popular SP kits to the most difficult and complex human sample types. By making the DNA isolation simpler, faster, and less expensive, we enable the routine analysis of solid tumors. Additionally, the new kit enables faster and streamlined processing of a variety of animal tissues, which we anticipate will greatly simplify the work of large consortia such as the Vertebrate Genome Project and work on model genome analysis for pharmaceutical research and development. Our next software release planned for later this summer is expected to make structural variant calling from non-human organisms more powerful and straightforward than before, and to maximize the benefit of our new DNA isolation kit.”
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About Bionano Genomics
Bionano is a genome analysis company providing tools and services based on its Saphyr system to scientists and clinicians conducting genetic research
and patient testing. Bionano’s Saphyr system is a platform for ultra-sensitive and ultra-specific structural variation detection that enables researchers and clinicians to accelerate the search for
new diagnostics and therapeutic targets and to streamline the study of changes in chromosomes, which is known as cytogenetics. The Saphyr system is comprised of an instrument, chip consumables,
reagents and a suite of data analysis tools, and genome analysis services to provide access to data generated by the Saphyr system for researchers who prefer not to adopt the Saphyr system in their
labs. For more information, visit www.bionanogenomics.com.