Teleflex Announces Positive Data Emphasizing the Effectiveness of the UroLift System Treatment for Enlarged Prostate Across Broad Patient Populations - Seite 2

“This is the largest and most comprehensive real-world investigation of a minimally invasive treatment for enlarged prostate, with results reaffirming those seen in controlled studies of the UroLift System,” said Mr. Kayes. “Additionally, these data indicate that the UroLift System provides rapid symptom relief to a wide range of patient cohorts without affecting safety outcomes.”

A presentation entitled 12-month symptom and urodynamic outcomes of the prostatic urethral lift in patients with acute urinary retention (PULSAR) was presented by Mark Rochester,* M.D., Norwich & Norfolk University Hospital. The study examined the feasibility of the UroLift System to treat patients with acute urinary retention.

Results from the study showed that patients experienced symptom relief at all time points following treatment with the UroLift System. Absolute IPSS scores were consistent with the pivotal L.I.F.T study, and quality of life outcomes were significantly better at the six and 12-month timepoints following treatment. Of the 52 patients included in the study, 60% were catheter-free by one month, and 73% by six months through study end. Additionally, 82% of patients were able to stop treatment with alpha blockers following treatment with the UroLift System and 87.5% of patients returned to normal activities 8.5 days after treatment. Results also demonstrated an improvement in urodynamic measurements among patients treated with the UroLift System, with a 38% reduction in Bladder Outlet Obstruction Index (BOOI). Finally, 83% of patients reported that they would recommend the procedure.

“The results from this study contribute to the robust portfolio of clinical evidence supporting the UroLift System treatment for patient subgroups that are not commonly seen in clinical trials,” said Mr. Rochester. “These findings highlight the safety and effectiveness of the UroLift System in treating men with acute urinary retention, offering this challenging patient population a viable alternative to long-term catheter management and major surgery.”

A third study — Meta-analysis comparison of sexual function outcomes after treatment with prostatic urethral lift or medical therapy — was presented by Claus Roehrborn,* M.D., University of Texas Southwestern Medical Center. Results from the analysis showed that patients treated with the UroLift System experienced significant improvements in ejaculatory function and erectile function through at least 24 months following treatment, while patients in some medical therapy groups did not experience significant average improvement at any timepoint.