Immunologist and Clinical Transplant Expert, Dolly B. Tyan, PhD, Joins Aditxt as Senior VP of Clinical Development - Transplantation - Seite 2

Dr. Tyan added, “My interest in joining Aditxt is our shared ambition to reach the ultimate goal of transplantation, which is to induce tolerance, where one transplanted organ lasts a lifetime without immunosuppression, as if it were the patient’s own. The Aditxt approach not only holds the promise of a breakthrough in this longstanding, intractable clinical problem, but if further advanced could solve another enormous worldwide problem. There are not enough donor organs for all those who need them; the donation rates are steady, but the need continues to grow annually. Part of the reason for this is that transplanted patients often lose their organs due to incompatibility and drug toxicity as well as the inability of immunosuppressive drugs to maintain control over the long term without themselves injuring the organs, leading to chronic rejection. These patients, if otherwise qualified after losing an organ, come back onto the waiting list, thus adding to the burgeoning numbers of waitlisted patients. I believe that the Aditxt approach can lead to One Organ for Life and this is what draws me to commit my time and experience into making this happen.”

Dolly B. Tyan, PhD, D(ABHI) obtained her PhD in Microbiology & Immunology from the University of California, Los Angeles, became a faculty member there in Pediatrics with an emphasis in Genetics, and was the Clinical Director of the Histocompatibility and Immunogenetics Laboratory at Cedars-Sinai Medical Center in Los Angeles for 19 years. She was a key faculty member in the immunogenetics of autoimmune disease including Type 1 diabetes and Inflammatory Bowel Disease profiling. Prior to this she led the Histocompatibility Lab at Stanford University for 15 years. She was recruited back to Stanford as Professor of Pathology and Medical Director of the Histocompatibility, Immunogenetics & Disease Profiling Laboratory in 2006, retiring in 2019. She was also the Director of Education & Innovation. 

Dr. Tyan has also been very active on the national stage. She was Vice President, President, and Immediate Past President of the American Society for Histocompatibility & Immunogenetics in 2000-2002. From 2000-2016, she served on multiple committees in the United Network for Organ Sharing, the U.S. Government’s contract organization responsible for all solid organ transplant allocation in the U.S. She served on the Executive Board, was Chair of the Histocompatibility Committee, and was a member of the Kidney/ Pancreas, Kidney, Operations, Strategic Planning, Policy Oversight, Quality Assurance and Standards, and Membership and Professional Standards committees.