Kapruvia (difelikefalin) recommended by England’s NICE for the treatment of adults with moderate-to-severe CKD-associated pruritus - Seite 3

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References:

1. Rayner, H. C., Larkina, M., Wang, M., Graham-Brown, M., van der Veer, S. N., Ecder, T., … Pisoni, R. L. (2017). International Comparisons of Prevalence, Awareness, and Treatment of Pruritus in People on Hemodialysis. Clinical journal of the American Society of Nephrology, 12(12), 2000–2007. doi:10.2215/CJN.03280317
2. Nidhi Sukul, Angelo Karaboyas, Philipp A. Csomor, Thilo Schaufler, Warren Wen, Frédérique Menzaghi, Hugh C. Rayner, Takeshi Hasegawa, Issa Al Salmi, Saeed M.G. Al-Ghamdi, Fitsum Guebre-Egziabher, Pablo-Antonio Urena-Torres, and Ronald L. Pisoni. Self-reported Pruritus and Clinical, Dialysis-Related, and Patient-Reported Outcomes in Hemodialysis Patients. Kidney Medicine 3(1):42-53. Published online 2020.
3. Mathur VS, et al. A longitudinal study of Uremic Pruritus in hemodialysis patients. Clin J Am Soc Nephrol. 2010; 5(8):1410-1419