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Thema: MHC Thema abonieren

Nachrichten zu "MHC"

19.09.2019
Bristol-Myers Squibb Research at ESMO Demonstrates Breadth of Oncology Development Program and Focus on Improving Overall Survival Across Multiple Cancers
...Number: #1251P Session: Poster Display Session 3 Session Time: Monday, September 30, 12-1 PM, Poster Area (Hall 4) Quantitative spatial profiling of lymphocyte-activation gene 3 (LAG-3)/major histocompatibility complex class II (MHC II) interaction in gastric and urothelial tumors Author: Hedvat Presentation Number: #2021P Session: Poster Display Session 1 Session Time: Saturday, September 28, 12-1 PM, Poster Area (Hall 4) Cross-Tumor Analysis of... [mehr]
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16.09.2019
Transgene Receives Approval from the French Health Authority (ANSM) to Initiate Two Clinical Trials of its Lead myvac Individualized Immunotherapy TG4050
...intelligence (AI), such as graph-based relational learning, which is combined with other sources of data to discover candidate neoantigen targets. NEC comprehensively evaluates the candidate neoantigens with a primary focus placed on its in-house MHC-binding affinity prediction trained on public and proprietary datasets. These allow NEC to effectively prioritize the numerous candidate neoantigens identified in a single patient. About Transgene Transgene (Euronext: TNG) is a publicly traded... [mehr]
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22.08.2019
TFS Financial Corporation Declares Dividend
...Chairman and CEO Marc A. Stefanski (Photo: Business Wire) Third Federal Savings and Loan Association of Cleveland, MHC (the “MHC”), the mutual holding company of the Company and owner of 227,119,132 shares, or 81.1% of the Company’s common stock outstanding, has waived its right to receive the dividend on its shares. On July 16, 2019, the MHC received the approval of its members (depositors and certain loan customers of the Association) with respect to the waiver of... [mehr]
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14.08.2019
HarborOne NorthEast Bancorp, Inc. Announces Completion of Stock Offering and Related Conversion
...“Company”) (NASDAQ: HONE), announced today that HarborOne Mutual Bancshares (the “MHC”) has completed its conversion from the mutual holding company to the stock holding company form of organization (the “Conversion”) and the Company’s related stock offering. As a result of the closing of the Conversion, the Company is now the holding company of HarborOne Bank (the “Bank”). The MHC and the Bank’s previous mid-tier holding company, HarborOne Bancorp, Inc. (“Old... [mehr]
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13.08.2019
HarborOne Bancorp, Inc. Announces Receipt of Regulatory Approvals and Expected Closing Date
...each existing share of the Company’s common stock held by public shareholders other than the MHC will be converted into the right to receive 1.7954 shares of New HarborOne common stock; cash will be paid in lieu of any fractional shares. The offering was oversubscribed in the community offering; accordingly, shares will be allocated in accordance with the terms of the Plan of Conversion of the MHC (the “Plan”), as described in the prospectus. Eligible depositors of the Bank (i.e.,... [mehr]
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01.04.2019
EQT Invests in MHC Asia, a Leading Healthcare Benefits Administrator in Southeast Asia
...The EQT Mid Market Asia III Fund ("EQT") has today announced its investment in MHC Asia Holdings Pte. Ltd. ("MHC" or "the Company"). Founded in 1994, MHC is a leading healthcare benefits administrator in Southeast Asia, offering approximately 800,000 corporate patients access to panel of over 1,200 clinics and processing about 1.8 million medical claims annually. Since its founding years, MHC has been striving to positively impact corporate managed healthcare in Singapore... [mehr]
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05.09.2014
Kearny MHC and Kearny Financial Corp. Announce Adoption of Plan of Conversion for Second-Step Stock Offering and New Foundation
...be named Kearny Financial Corp. The shares of common stock of the Company held by persons other than the MHC will be converted into shares of common stock of the new stock holding company pursuant to an exchange ratio designed to preserve the approximate percentage ownership interests of such persons. The shares of the Company held by the MHC will be cancelled and the amount of the MHC's ownership interest in the Company will be sold through the second-step stock offering. In the stock... [mehr]
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19.12.2014
Kearny MHC and Kearny Financial Corp. Provide Update on Progress of Second-Step Stock Offering
KEARNY, NJ--(Marketwired - Dec 19, 2014) - Kearny MHC (the "MHC") and Kearny Financial Corp, a federal corporation (the "Company") (NASDAQ: KRNY), the holding company for Kearny Federal Savings Bank (the "Bank"), provided an update on the progress of its proposed reorganization into a new stock holding company and second-step stock offering of new shares of common stock. As a result of the passage of time from the initial date of filing of the... [mehr]
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29.11.2013
CAPREIT Completes Acquisition of 2,308 MHC Sites in New Brunswick
...on the Petitcodiac River near Moncton, includes 16.5 acres of undeveloped land for future expansion. CAPREIT paid approximately $69.0 million for the MHC portfolio satisfied initially in cash through CAPREIT's Acquisition and Operating credit facility. With the completion of this acquisition, CAPREIT's total MHC portfolio now aggregates 6,178 land lease sites located in New Brunswick, Prince Edward Island, Ontario, Saskatchewan, Alberta and British Columbia representing... [mehr]
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11.05.2016
CAPREIT Further Diversifies Portfolio with Purchase of High Quality Townhome and MHC Properties
...of our property portfolio, adding high quality townhome units and MHC sites in strong geographic markets with high demand for rental accommodation," commented Thomas Schwartz, President and CEO. "Townhomes with multiple bedrooms are in high demand in the GTA, and we expect the property to make a strong and growing contribution to our results. The Fort St. John area is also growing, and these high quality MHC sites are sure to remain full for years to come." ABOUT CAPREIT... [mehr]
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01.04.2019
EQT Invests in MHC Asia, a Leading Healthcare Benefits Administrator in Southeast Asia
...The EQT Mid Market Asia III Fund ("EQT") has today announced its investment in MHC Asia Holdings Pte. Ltd. ("MHC" or "the Company"). Founded in 1994, MHC is a leading healthcare benefits administrator in Southeast Asia, offering approximately 800,000 corporate patients access to panel of over 1,200 clinics and processing about 1.8 million medical claims annually. Since its founding years, MHC has been striving to positively impact corporate managed healthcare in Singapore... [mehr]
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05.09.2014
Kearny MHC and Kearny Financial Corp. Announce Adoption of Plan of Conversion for Second-Step Stock Offering and New Foundation
...be named Kearny Financial Corp. The shares of common stock of the Company held by persons other than the MHC will be converted into shares of common stock of the new stock holding company pursuant to an exchange ratio designed to preserve the approximate percentage ownership interests of such persons. The shares of the Company held by the MHC will be cancelled and the amount of the MHC's ownership interest in the Company will be sold through the second-step stock offering. In the stock... [mehr]
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19.12.2014
Kearny MHC and Kearny Financial Corp. Provide Update on Progress of Second-Step Stock Offering
KEARNY, NJ--(Marketwired - Dec 19, 2014) - Kearny MHC (the "MHC") and Kearny Financial Corp, a federal corporation (the "Company") (NASDAQ: KRNY), the holding company for Kearny Federal Savings Bank (the "Bank"), provided an update on the progress of its proposed reorganization into a new stock holding company and second-step stock offering of new shares of common stock. As a result of the passage of time from the initial date of filing of the... [mehr]
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29.11.2013
CAPREIT Completes Acquisition of 2,308 MHC Sites in New Brunswick
...on the Petitcodiac River near Moncton, includes 16.5 acres of undeveloped land for future expansion. CAPREIT paid approximately $69.0 million for the MHC portfolio satisfied initially in cash through CAPREIT's Acquisition and Operating credit facility. With the completion of this acquisition, CAPREIT's total MHC portfolio now aggregates 6,178 land lease sites located in New Brunswick, Prince Edward Island, Ontario, Saskatchewan, Alberta and British Columbia representing... [mehr]
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11.05.2016
CAPREIT Further Diversifies Portfolio with Purchase of High Quality Townhome and MHC Properties
...of our property portfolio, adding high quality townhome units and MHC sites in strong geographic markets with high demand for rental accommodation," commented Thomas Schwartz, President and CEO. "Townhomes with multiple bedrooms are in high demand in the GTA, and we expect the property to make a strong and growing contribution to our results. The Fort St. John area is also growing, and these high quality MHC sites are sure to remain full for years to come." ABOUT CAPREIT... [mehr]
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Diskussionen zu "MHC"

Rohstoff-Explorer: Research oder Neuvorstellung19.02.2018
...mglw; immensem Potenzial haben möchten; nehmen Sie doch bspw. an der HC MHC Diskussion teil. Ganz reale Geschichte. Developing forward stellen sich eben noch div Fragen. meinste die? http://manhattancorp.com.au/ scheint historisch resourcenbasiert was vorzuliegen. warum ist die letzte meldung aus 2012? sieht recht interessant aus. guter tipp, danke! https://hotcopper.com.au/asx/mhc/ https://hotcopper.com.au/asx/mhc/ [mehr]
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Exelixis....ein schlafender Riese? USD 3.40 am 14.5.201430.05.2016
...demonstrated monotherapy activity in a multitude of human tumor types. However, response rates in microsatellite stable (MSS) CRCs have been lower than in other indications. In preclinical models, targeted inhibition of MEK leads to upregulation of MHC I on tumor cells, induces intratumoral T-cell infiltration and enhances anti-PDL1 activity. We therefore conducted a Phase Ib study combining cobi (MEK inhibitor) and atezo in patients (pts) with advanced solid tumors. Methods: Cobi was escalated... [mehr]
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Exelixis....ein schlafender Riese? USD 3.40 am 14.5.201418.05.2016
...demonstrated monotherapy activity in a multitude of human tumor types. However, response rates in microsatellite stable (MSS) CRCs have been lower than in other indications. In preclinical models, targeted inhibition of MEK leads to upregulation of MHC I on tumor cells, induces intratumoral T-cell infiltration and enhances anti-PDL1 activity. We therefore conducted a Phase Ib study combining cobi (MEK inhibitor) and atezo in patients (pts) with advanced solid tumors. Methods: Cobi was escalated... [mehr]
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Morphosys: Setzen auf marktreife Partnerprojekte und dicke Meilensteine28.10.2015
...von Morphosys sein ? https://en.wikipedia.org/wiki/LAG525 Das Target gefällt mir. Checkpoint Inhibitor für Immuntherapie. Wobei ich bei dessen main ligand "MHC class II" gleich an das Target von 1D09C3, den eingestellten Biotech-AK denken musste ("1D09C3 is an anti-MHC class II monoclonal antibody. "). ----------- LAG3's main ligand is MHC class II, to which it binds with higher affinity than CD4.[9] The protein negatively regulates cellular proliferation, activation, and homeostasis of T cells,... [mehr]
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Sellas Life Sciences Group (ehemals Galena Biopharma)08.04.2015
...NeuVax as well as an update of the phase III trial and additional studies evaluating a novel combination immunotherapy strategy combining the vaccine with trastuzumab. In addition, phase II trials evaluating GP2, a second MHC class I vaccine and AE37, an MHC class II vaccine have recently reported their primary endpoint analyses and these results will be discussed. CEO Schwartz (am gleichen Tag) in New York Galena Biopharma, Inc. (Nasdaq:GALE), a biopharmaceutical company developing and... [mehr]
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GPC-Biotech: Qualitätstitel mit enormen Zukunftspot. - KZ: 25,00 - 35,00 Euro !13.11.2002
...Aktivität von Protein-Kinase C, einer Proteinfamilie, die mitverantwortlich für die Regulation des Wachstums und des Zelltodes von Krebszellen ist. MHC-Klasse-II-Antikörper Dieses Programm beruht auf der Erkenntnis, dass bestimmte monoklonale Antikörper, die anMHC-Klasse-II-Rezeptoren binden, das Absterben aktivierter, sich vermehrender MHC-Klasse-ll-positiver Lymphom- bzw. Leukämiezellen, wie z. B. B-Zell-Lymphomen, verursachen können. Dabei werden aber gesunde, nicht aktivierte Zellen... [mehr]
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BILDUNG ... oder warum sich gebildete Menschen nicht verstehen22.03.2001
...umgekehrt), setzt sich aber auch im späteren Leben fort. Möglich wird die Identifizierung naher genetischer Verwandter durch die körpereigene Signatur des MHC (major histocompatibility complex), welches dem Immunsystem des Körpers hilft, fremde Zellen von körpereigenen zu unterscheiden. Die bei jedem Menschen unterscheidbaren MHC-Moleküle werden, durch die Prozesse des Stoffwechsels bedingt, kontinuierlich in ihre Bestandteile aufgelöst und wandern mit der Körperflüssigkeit in die... [mehr]
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Corixa (CRXA)-noch nie gehört? dann mal anschauen11.04.2000
...peptide sequence (amino acids 57-76) from the Beta chain of the specific MHC class II molecules genetically linked to RA, and includes a ``shared epitope,`` that is common to approximately 90 percent of RA patients. In autoimmune diseases like rheumatoid arthritis, the body erroneously recognizes components of cells or tissues as foreign antigens. These autoantigens are presented to the immune system by disease-linked MHC class II molecules on the surface of antigen-presenting cells (APC). The... [mehr]
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>>>> Die Zeit ist reif für ----->> HEPALIFE12.09.2004
...between 6.6 million and 66 copies per sample. Pig MHC class I gene primers and probe were developed as internal controls for porcine cellular DNA (37, 38). Primers and probe were derived from the pig MHC gene and are as follows: MHC sense, 5`-GCCCTGGGCTTCTACCCTAA-3`; MHC antisense, 5`-TCTCAGGGTGAGTGGCTCCT-3`; probe, 5`-6FAM-CCAGGACCAGAGCCAGGACATGGAGCTCGT-TAMRA-3`. Quantitative sensitivity was 3 copies per reaction. Quantification of pig MHC served as a control for the nucleic acid input amount... [mehr]
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MOLOGEN - FORUM 1703.05.2001
...are able to present tumor antigens to immunologic effector cells. MHC class II molecules on DC surfaces play an important role in priming effector cells against tumor cells and their antigens. The transactivator CIITA (MHC class II transactivator) is a non-DNA-binding transactivator, which regulates the expression of MHC class II, HLA-DM, and invariant chain and behaves as a master controller of constitutive and inducible MHC class II gene activation. Here, we transfected DCs with the CIITA gene... [mehr]
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GPC-Biotech: Qualitätstitel mit enormen Zukunftspot. - KZ: 25,00 - 35,00 Euro !13.11.2002
...Aktivität von Protein-Kinase C, einer Proteinfamilie, die mitverantwortlich für die Regulation des Wachstums und des Zelltodes von Krebszellen ist. MHC-Klasse-II-Antikörper Dieses Programm beruht auf der Erkenntnis, dass bestimmte monoklonale Antikörper, die anMHC-Klasse-II-Rezeptoren binden, das Absterben aktivierter, sich vermehrender MHC-Klasse-ll-positiver Lymphom- bzw. Leukämiezellen, wie z. B. B-Zell-Lymphomen, verursachen können. Dabei werden aber gesunde, nicht aktivierte Zellen... [mehr]
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BILDUNG ... oder warum sich gebildete Menschen nicht verstehen22.03.2001
...umgekehrt), setzt sich aber auch im späteren Leben fort. Möglich wird die Identifizierung naher genetischer Verwandter durch die körpereigene Signatur des MHC (major histocompatibility complex), welches dem Immunsystem des Körpers hilft, fremde Zellen von körpereigenen zu unterscheiden. Die bei jedem Menschen unterscheidbaren MHC-Moleküle werden, durch die Prozesse des Stoffwechsels bedingt, kontinuierlich in ihre Bestandteile aufgelöst und wandern mit der Körperflüssigkeit in die... [mehr]
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Corixa (CRXA)-noch nie gehört? dann mal anschauen11.04.2000
...peptide sequence (amino acids 57-76) from the Beta chain of the specific MHC class II molecules genetically linked to RA, and includes a ``shared epitope,`` that is common to approximately 90 percent of RA patients. In autoimmune diseases like rheumatoid arthritis, the body erroneously recognizes components of cells or tissues as foreign antigens. These autoantigens are presented to the immune system by disease-linked MHC class II molecules on the surface of antigen-presenting cells (APC). The... [mehr]
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>>>> Die Zeit ist reif für ----->> HEPALIFE12.09.2004
...between 6.6 million and 66 copies per sample. Pig MHC class I gene primers and probe were developed as internal controls for porcine cellular DNA (37, 38). Primers and probe were derived from the pig MHC gene and are as follows: MHC sense, 5`-GCCCTGGGCTTCTACCCTAA-3`; MHC antisense, 5`-TCTCAGGGTGAGTGGCTCCT-3`; probe, 5`-6FAM-CCAGGACCAGAGCCAGGACATGGAGCTCGT-TAMRA-3`. Quantitative sensitivity was 3 copies per reaction. Quantification of pig MHC served as a control for the nucleic acid input amount... [mehr]
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MOLOGEN - FORUM 1703.05.2001
...are able to present tumor antigens to immunologic effector cells. MHC class II molecules on DC surfaces play an important role in priming effector cells against tumor cells and their antigens. The transactivator CIITA (MHC class II transactivator) is a non-DNA-binding transactivator, which regulates the expression of MHC class II, HLA-DM, and invariant chain and behaves as a master controller of constitutive and inducible MHC class II gene activation. Here, we transfected DCs with the CIITA gene... [mehr]
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