Multicell Technologies Inc. - 500 Beiträge pro Seite
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ISIN: US62544S2005 · WKN: A0ET6A · Symbol: MCET
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MultiCell Technologies' Proprietary Breakthrough Anti-Cancer Therapy Shown to Prevent Recurrence of Cancer
Company's MCT-465 Drug Combined with Patented Immune-System Modulation Technology Prevents New Tumor Growth in Preclinical Animal Model
Last Update: 6:30 AM ET Jan 11, 2007
SAN DIEGO, Jan 11, 2007 (BUSINESS WIRE) -- MultiCell Technologies, Inc. (MCET :
multicell technologies inc com new
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Last: 0.230.000.00%
9:54am 01/26/2007
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Sponsored by:
MCET0.23, 0.00, 0.0% ) , developing first-in-class drugs based on advanced immune system modulation technologies, has announced that the Company's proprietary anti-cancer technologies not only eradicated cancer in animal studies but also prevented the recurrence of the disease.
The research focused on a unique combination therapy based on MCET's MCT-465 drug candidate co-administered with IgNP, a proprietary MCET immune-modulation drug. It found that the Company's combination therapy not only destroyed cancerous tumors but conferred protection against new tumor growth, or recurrence of the disease.
"In cancer treatment, destroying the tumor is half the battle, while the other half is preventing the cancer from recurring," said Dr. Stephen Chang, Chief Executive Officer of MultiCell Technologies. "These findings are important because they demonstrate that our drug can prevent the cancer from returning. Preventing cancer from recurring in animal models is an important benchmark in developing new cancer therapeutics and toward prolonging life."
Specifically, the research examined the co-administration of MCT-465, a Toll-like Receptor (TLR) agonist and IgNP, the Company's patented antigen presenting immunoglobulin therapeutic.
"Previously we demonstrated conclusively that co-administration of MCT-465 with our patented antigen-presenting immunoglobulin therapeutic ('IgNP') completely destroyed tumors and prevented mortality," said Dr. Chang. "Now we have demonstrated that this same therapy prevents the recurrence of secondary cancers in animal models. Additionally, the T-cells from the immunized mice displayed a long-lasting, increased production of certain cytokines which are key players in the destruction of tumors."
The Company's scientists demonstrated that mice previously treated with the IgNP/MCT-465 combination therapy which demonstrated tumor remission, remained immune to the development of new cancers even when challenged with a new tumorigenic dose of homologous tumor cells. The challenged mice were completely protected against secondary cancers, whereas the control group of mice developed tumors with a 100% rate.
"Our work in this area was recently published in the Journal of Immunology, and we have filed several patents covering the technology," noted Dr. Chang.
MultiCell is an innovator in the science of modulating the human immune system with unique platform technologies, focusing on the development of breakthrough drugs to treat serious diseases, including multiple sclerosis, type-1 diabetes, influenza, and cancer.
About MultiCell Technologies, Inc.
MultiCell Technologies, Inc. is an integrated biopharmaceutical company committed to the development of breakthrough therapeutics based on a portfolio of therapeutic candidates and patented drug development technology. MultiCell's drug development program is focused on modulation of the immune system.
MultiCell's therapeutic pipeline includes drug candidates, some of which are in various advanced stages of human clinical trials. These therapies include:
-- MCT-125 for the treatment of chronic fatigue in MS patients. MCT-125 completed a Phase II clinical trial and demonstrated significant efficacy in reducing chronic fatigue in MS patients. There is no drug specifically approved for the treatment of chronic fatigue in MS patients anywhere in the world.
-- MCT-175 for the treatment of relapsing-remitting MS. MCT-175, in preclinical development for the treatment of relapsing-remitting MS, targets disease specific autoaggressive T-cells that destroy the myelin sheath of nerve cells. MCT-175 successfully ameliorated the disease in animal models.
-- MCT-275 for the treatment of type-1 diabetes. MCT-275, in preclinical development, targets disease-specific autoaggressive T-cells that destroy insulin producing cells in the pancreas. MCT-275 completely reversed the type-1 diabetic phenotype and prolonged life in animal models.
-- MCT-465 in an adjuvant therapy for the treatment of virus infection and cancer. MCT-465 in preclinical studies successfully reduced pulmonary influenza virus levels 1,000-fold in animal models, and has demonstrated effectiveness in reducing virus levels of HIV and HCV in animal models. MCT-465 in preclinical studies successfully eliminated certain types of tumors in animal models.
The Company also holds unique cell-based technology for use in drug discovery screening applications, and is a leading producer of the cell lines needed by the biotechnology industry to develop new drugs. For more information about MultiCell Technologies, please visit http://www.multicelltech.com.
http://www.multicelltech.com/
Partner
http://www.multicelltech.com/partnerships.html
MultiCell Technologies' Proprietary Breakthrough Anti-Cancer Therapy Shown to Prevent Recurrence of Cancer
Company's MCT-465 Drug Combined with Patented Immune-System Modulation Technology Prevents New Tumor Growth in Preclinical Animal Model
Last Update: 6:30 AM ET Jan 11, 2007
SAN DIEGO, Jan 11, 2007 (BUSINESS WIRE) -- MultiCell Technologies, Inc. (MCET :
multicell technologies inc com new
News , chart, profile, more
Last: 0.230.000.00%
9:54am 01/26/2007
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Sponsored by:
MCET0.23, 0.00, 0.0% ) , developing first-in-class drugs based on advanced immune system modulation technologies, has announced that the Company's proprietary anti-cancer technologies not only eradicated cancer in animal studies but also prevented the recurrence of the disease.
The research focused on a unique combination therapy based on MCET's MCT-465 drug candidate co-administered with IgNP, a proprietary MCET immune-modulation drug. It found that the Company's combination therapy not only destroyed cancerous tumors but conferred protection against new tumor growth, or recurrence of the disease.
"In cancer treatment, destroying the tumor is half the battle, while the other half is preventing the cancer from recurring," said Dr. Stephen Chang, Chief Executive Officer of MultiCell Technologies. "These findings are important because they demonstrate that our drug can prevent the cancer from returning. Preventing cancer from recurring in animal models is an important benchmark in developing new cancer therapeutics and toward prolonging life."
Specifically, the research examined the co-administration of MCT-465, a Toll-like Receptor (TLR) agonist and IgNP, the Company's patented antigen presenting immunoglobulin therapeutic.
"Previously we demonstrated conclusively that co-administration of MCT-465 with our patented antigen-presenting immunoglobulin therapeutic ('IgNP') completely destroyed tumors and prevented mortality," said Dr. Chang. "Now we have demonstrated that this same therapy prevents the recurrence of secondary cancers in animal models. Additionally, the T-cells from the immunized mice displayed a long-lasting, increased production of certain cytokines which are key players in the destruction of tumors."
The Company's scientists demonstrated that mice previously treated with the IgNP/MCT-465 combination therapy which demonstrated tumor remission, remained immune to the development of new cancers even when challenged with a new tumorigenic dose of homologous tumor cells. The challenged mice were completely protected against secondary cancers, whereas the control group of mice developed tumors with a 100% rate.
"Our work in this area was recently published in the Journal of Immunology, and we have filed several patents covering the technology," noted Dr. Chang.
MultiCell is an innovator in the science of modulating the human immune system with unique platform technologies, focusing on the development of breakthrough drugs to treat serious diseases, including multiple sclerosis, type-1 diabetes, influenza, and cancer.
About MultiCell Technologies, Inc.
MultiCell Technologies, Inc. is an integrated biopharmaceutical company committed to the development of breakthrough therapeutics based on a portfolio of therapeutic candidates and patented drug development technology. MultiCell's drug development program is focused on modulation of the immune system.
MultiCell's therapeutic pipeline includes drug candidates, some of which are in various advanced stages of human clinical trials. These therapies include:
-- MCT-125 for the treatment of chronic fatigue in MS patients. MCT-125 completed a Phase II clinical trial and demonstrated significant efficacy in reducing chronic fatigue in MS patients. There is no drug specifically approved for the treatment of chronic fatigue in MS patients anywhere in the world.
-- MCT-175 for the treatment of relapsing-remitting MS. MCT-175, in preclinical development for the treatment of relapsing-remitting MS, targets disease specific autoaggressive T-cells that destroy the myelin sheath of nerve cells. MCT-175 successfully ameliorated the disease in animal models.
-- MCT-275 for the treatment of type-1 diabetes. MCT-275, in preclinical development, targets disease-specific autoaggressive T-cells that destroy insulin producing cells in the pancreas. MCT-275 completely reversed the type-1 diabetic phenotype and prolonged life in animal models.
-- MCT-465 in an adjuvant therapy for the treatment of virus infection and cancer. MCT-465 in preclinical studies successfully reduced pulmonary influenza virus levels 1,000-fold in animal models, and has demonstrated effectiveness in reducing virus levels of HIV and HCV in animal models. MCT-465 in preclinical studies successfully eliminated certain types of tumors in animal models.
The Company also holds unique cell-based technology for use in drug discovery screening applications, and is a leading producer of the cell lines needed by the biotechnology industry to develop new drugs. For more information about MultiCell Technologies, please visit http://www.multicelltech.com.
http://www.multicelltech.com/
Partner
http://www.multicelltech.com/partnerships.html
MultiCell Technologies Announces Progress for MCT-125's Anticipated Phase IIb Clinical Trial
Meeting with British Health Authorities Allows Company to Further Clinical Trials for Lead Therapeutics Program Targeting Multibillion Dollar Worldwide Market
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Last Update: 3:30 AM ET Feb 6, 2007
SAN DIEGO, Feb 06, 2007 (BUSINESS WIRE) -- MultiCell Technologies, Inc. (MCET :
multicell technologies inc com new
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Last: 0.21+0.01+2.44%
12:27am 02/06/2007
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Sponsored by:
MCET0.21, +0.01, +2.4% ) , developing first-in-class drugs based on advanced immune system modulation technologies, announced today it has received the formal Minutes from its December 1, 2006 milestone meeting with the Medicines and Healthcare Products Regulatory Agency UK (MHRA). The MHRA meeting cleared the way for MultiCell to prepare and submit the Clinical Trial Authorization (CTA) application, retain the MS centers where the clinical study will be conducted, and complete the manufacturing and formulation procedures for the Company's lead therapeutics program, MCT-125.
If MCT-125 is approved for the treatment of fatigue in MS patients by the MHRA, the FDA, and other such regulatory agencies, and is successfully commercialized, MultiCell estimates MCT-125 could generate up to $3 billion in cumulative worldwide sales during the time MCT-125 is under patent protection.
"The MHRA was very helpful in clarifying that our current preclinical data package and proposed clinical trial design is acceptable, which allows us to prepare and file our CTA application," said Dr. Stephen Chang, President and Chief Executive Officer of Multicell Technologies. "The results from this meeting are significant since MHRA stated we do not have to conduct additional preclinical testing of MCT-125 prior to filing our application requesting allowance to proceed with our planned Phase IIb clinical trial."
The purpose of the meeting with MHRA was to present the Company's proposed clinical development plan for MCT-125 for the treatment of chronic fatigue in multiple sclerosis (MS) patients, and to seek guidance from MHRA with respect to the proposed Phase IIb clinical trial design and accompanying preclinical data package.
In an earlier 138 patient, multi-center, double-blind placebo controlled Phase II clinical trial conducted in the UK by Amarin Corporation, MCT-125 (then known as LAX-202) demonstrated efficacy in reducing the levels of fatigue in MS patients enrolled in the study. MCT-125 proved to be effective within 4 weeks of the first daily oral dosing, and showed efficacy in MS patients who were moderately as well as severely affected. MCT-125 demonstrated efficacy in all MS patient sub-populations including relapsing-remitting, secondary progressive and primary progressive.
MultiCell is an innovator in the science of modulating the human immune system with unique platform technologies, focusing on the development of breakthrough drugs to treat serious diseases, including multiple sclerosis, type-1 diabetes, influenza, and cancer.
About MultiCell Technologies, Inc.
MultiCell Technologies, Inc. is an integrated biopharmaceutical company committed to the development of breakthrough therapeutics based on a portfolio of therapeutic candidates and patented drug development technology. MultiCell's drug development program is focused on modulation of the immune system.
MultiCell's therapeutic pipeline includes drug candidates some of which are in various advanced stages of human clinical trials. These therapies include:
-- MCT-125 for the treatment of chronic fatigue in MS patients.
-- MCT-175 for the treatment of relapsing-remitting MS.
-- MCT-275 for the treatment of type-1 diabetes.
-- MCT-465 in an adjuvant therapy for the treatment of virus infection and cancer.
The Company also holds unique cell-based technology for use in drug discovery screening applications, and is a leading producer of the cell lines needed by the biotechnology industry to develop new drugs. For more information about MultiCell Technologies, please visit http://www.multicelltech.com.
For investor information about MultiCell, please visit http://www.trilogy-capital.com/tcp/multicell.
Caution Regarding Forward-Looking Statements
Any statements in this press release about MultiCell's expectations, beliefs, plans, objectives, assumptions or future events or performance are not historical facts and are forward-looking statements for purposes of the Private Securities Litigation Reform Act of 1995 (the "Act"). These statements are often, but not always, made through the use of words or phrases such as "believe," "will," "expect," "anticipate," "estimate," "intend," "plan," "forecast," "could," and "would." Examples of such forward looking statements include statements regarding the timing, design, scope, and anticipated results of our clinical development of MCT-125. MultiCell bases these forward-looking statements on current expectations about future events. They involve known and unknown risks, uncertainties and assumptions that may cause actual results, levels of activity, performance or achievements to differ materially from those expressed or implied by any forward-looking statement. Some of the risks, uncertainties and assumptions that could cause actual results to differ materially from estimates or projections in the forward-looking statement include, but are not limited to, the risk that we might not achieve our anticipated clinical development milestones, receive regulatory approval, or successfully commercialize MCT-125 as expected, the market for our products will not grow as expected, and the risk that our products will not achieve expectations. For additional information about risks and uncertainties MultiCell faces, see documents MultiCell files with the SEC, including MultiCell's report on Form 10-KSB for the fiscal year ended November 30, 2005, and all our quarterly and other periodic SEC filings. MultiCell claims the protection of the safe harbor for forward-looking statements under the Act and each assume no obligation and expressly disclaim any duty to update any forward-looking statement to reflect events or circumstances after the date of this news release or to reflect the occurrence of subsequent events.
SOURCE: MultiCell Technologies, Inc.
MultiCell Technologies, Inc. Dr. Stephen Chang, CEO, 401-333-0610 MCETInvestor@MultiCelltech.com Copyright Business Wire 2007 End of Story
Meeting with British Health Authorities Allows Company to Further Clinical Trials for Lead Therapeutics Program Targeting Multibillion Dollar Worldwide Market
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Last Update: 3:30 AM ET Feb 6, 2007
SAN DIEGO, Feb 06, 2007 (BUSINESS WIRE) -- MultiCell Technologies, Inc. (MCET :
multicell technologies inc com new
News , chart, profile, more
Last: 0.21+0.01+2.44%
12:27am 02/06/2007
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Sponsored by:
MCET0.21, +0.01, +2.4% ) , developing first-in-class drugs based on advanced immune system modulation technologies, announced today it has received the formal Minutes from its December 1, 2006 milestone meeting with the Medicines and Healthcare Products Regulatory Agency UK (MHRA). The MHRA meeting cleared the way for MultiCell to prepare and submit the Clinical Trial Authorization (CTA) application, retain the MS centers where the clinical study will be conducted, and complete the manufacturing and formulation procedures for the Company's lead therapeutics program, MCT-125.
If MCT-125 is approved for the treatment of fatigue in MS patients by the MHRA, the FDA, and other such regulatory agencies, and is successfully commercialized, MultiCell estimates MCT-125 could generate up to $3 billion in cumulative worldwide sales during the time MCT-125 is under patent protection.
"The MHRA was very helpful in clarifying that our current preclinical data package and proposed clinical trial design is acceptable, which allows us to prepare and file our CTA application," said Dr. Stephen Chang, President and Chief Executive Officer of Multicell Technologies. "The results from this meeting are significant since MHRA stated we do not have to conduct additional preclinical testing of MCT-125 prior to filing our application requesting allowance to proceed with our planned Phase IIb clinical trial."
The purpose of the meeting with MHRA was to present the Company's proposed clinical development plan for MCT-125 for the treatment of chronic fatigue in multiple sclerosis (MS) patients, and to seek guidance from MHRA with respect to the proposed Phase IIb clinical trial design and accompanying preclinical data package.
In an earlier 138 patient, multi-center, double-blind placebo controlled Phase II clinical trial conducted in the UK by Amarin Corporation, MCT-125 (then known as LAX-202) demonstrated efficacy in reducing the levels of fatigue in MS patients enrolled in the study. MCT-125 proved to be effective within 4 weeks of the first daily oral dosing, and showed efficacy in MS patients who were moderately as well as severely affected. MCT-125 demonstrated efficacy in all MS patient sub-populations including relapsing-remitting, secondary progressive and primary progressive.
MultiCell is an innovator in the science of modulating the human immune system with unique platform technologies, focusing on the development of breakthrough drugs to treat serious diseases, including multiple sclerosis, type-1 diabetes, influenza, and cancer.
About MultiCell Technologies, Inc.
MultiCell Technologies, Inc. is an integrated biopharmaceutical company committed to the development of breakthrough therapeutics based on a portfolio of therapeutic candidates and patented drug development technology. MultiCell's drug development program is focused on modulation of the immune system.
MultiCell's therapeutic pipeline includes drug candidates some of which are in various advanced stages of human clinical trials. These therapies include:
-- MCT-125 for the treatment of chronic fatigue in MS patients.
-- MCT-175 for the treatment of relapsing-remitting MS.
-- MCT-275 for the treatment of type-1 diabetes.
-- MCT-465 in an adjuvant therapy for the treatment of virus infection and cancer.
The Company also holds unique cell-based technology for use in drug discovery screening applications, and is a leading producer of the cell lines needed by the biotechnology industry to develop new drugs. For more information about MultiCell Technologies, please visit http://www.multicelltech.com.
For investor information about MultiCell, please visit http://www.trilogy-capital.com/tcp/multicell.
Caution Regarding Forward-Looking Statements
Any statements in this press release about MultiCell's expectations, beliefs, plans, objectives, assumptions or future events or performance are not historical facts and are forward-looking statements for purposes of the Private Securities Litigation Reform Act of 1995 (the "Act"). These statements are often, but not always, made through the use of words or phrases such as "believe," "will," "expect," "anticipate," "estimate," "intend," "plan," "forecast," "could," and "would." Examples of such forward looking statements include statements regarding the timing, design, scope, and anticipated results of our clinical development of MCT-125. MultiCell bases these forward-looking statements on current expectations about future events. They involve known and unknown risks, uncertainties and assumptions that may cause actual results, levels of activity, performance or achievements to differ materially from those expressed or implied by any forward-looking statement. Some of the risks, uncertainties and assumptions that could cause actual results to differ materially from estimates or projections in the forward-looking statement include, but are not limited to, the risk that we might not achieve our anticipated clinical development milestones, receive regulatory approval, or successfully commercialize MCT-125 as expected, the market for our products will not grow as expected, and the risk that our products will not achieve expectations. For additional information about risks and uncertainties MultiCell faces, see documents MultiCell files with the SEC, including MultiCell's report on Form 10-KSB for the fiscal year ended November 30, 2005, and all our quarterly and other periodic SEC filings. MultiCell claims the protection of the safe harbor for forward-looking statements under the Act and each assume no obligation and expressly disclaim any duty to update any forward-looking statement to reflect events or circumstances after the date of this news release or to reflect the occurrence of subsequent events.
SOURCE: MultiCell Technologies, Inc.
MultiCell Technologies, Inc. Dr. Stephen Chang, CEO, 401-333-0610 MCETInvestor@MultiCelltech.com Copyright Business Wire 2007 End of Story
MultiCell Technologies Announces Prospective Cancer Treatment Drug
MCT-475 Targets Multibillion Dollar Worldwide Market for the Treatment of Colorectal Cancer, A Leading Cause of Death Among Cancer Patients
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Last Update: 3:30 AM ET Feb 15, 2007
SAN DIEGO, Feb 15, 2007 (BUSINESS WIRE) -- MultiCell Technologies, Inc. (MCET :
multicell technologies inc com new
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Last: 0.200.000.00%
12:24am 02/15/2007
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Sponsored by:
MCET0.20, 0.00, 0.0% ) , developing first-in-class drugs based on advanced immune system modulation technologies, announced today it has reached a developmental milestone to advance its colorectal cancer lead therapeutic candidate to preclinical development status. MCT-475 is indicated as a prospective treatment for metastatic colorectal cancer, the third leading cause of death among both men and women in the United States. MCT-475 is a patent pending antigen-presenting immunoglobulin therapeutic which is intended to be co-administered with MCT-465, a Toll-like Receptor (TLR) agonist.
"Previously we demonstrated that co-administration of MCT-465 with our patent pending antigen-presenting immunoglobulin therapeutic IgNP prototype completely destroyed tumors, and prevented mortality and recurrence in animal models," said Dr. Stephen Chang, President and CEO of Multicell Technologies. "MCT-475 is designed to activate the adaptive immune system to target unique structural motifs located on the surface of human metastatic colorectal cancer cells, while MCT-465 is designed to activate the innate immune system through TLR signaling. Working together, MCT-475 and MCT-465 stimulate the body's immune system to target and kill metastatic colorectal cells."
Colorectal cancer is the third most common cancer in both men and women in the United States, and remains the third leading cause of death from cancer in the United States. The American Cancer Society estimates that about 145,000 new cases of colorectal cancer were reported in 2005.
According to the World Health Organization's April 2003 report on global cancer rates more than 940,000 new cases of colorectal cancer, and nearly 500,000 deaths are reported worldwide each year. The overall 5-year survival rate from the various types of colorectal cancer is approximately 60%, whereas for metastatic colorectal cancer, the 5-year survival rate is about 5%.
Risk factors for metastatic cancer include age, a diet rich in fat and cholesterol, inflammatory bowel disease, and genetic predisposition. If detected early, colorectal cancer is curable by surgery. Chemotherapy can prolong survival in patients where the disease has metastasized and reached the lymph nodes.
MultiCell is an innovator in the science of modulating the human immune system with unique platform technologies, focusing on the development of breakthrough drugs to treat serious diseases, including multiple sclerosis, type-1 diabetes, influenza, and cancer.
About MultiCell Technologies, Inc.
MultiCell Technologies, Inc. is an integrated biopharmaceutical company committed to the development of breakthrough therapeutics based on a portfolio of therapeutic candidates and patented drug development technology. MultiCell's drug development program is focused on modulation of the immune system.
MultiCell's therapeutic pipeline includes drug candidates some of which are in various advanced stages of human clinical trials. These therapies include:
-- MCT-125 for the treatment of chronic fatigue in MS patients.
-- MCT-175 for the treatment of relapsing-remitting MS.
-- MCT-275 for the treatment of type-1 diabetes.
-- MCT-465 an adjuvant therapy for the treatment of virus infection and cancer.
-- MCT-475 for the treatment of colorectal cancer.
The Company also holds unique cell-based technology for use in drug discovery screening applications, and is a leading producer of the cell lines needed by the biotechnology industry to develop new drugs. For more information about MultiCell Technologies, please visit http://www.multicelltech.com.
Caution Regarding Forward-Looking Statements
Any statements in this press release about MultiCell's expectations, beliefs, plans, objectives, assumptions or future events or performance are not historical facts and are forward-looking statements for purposes of the Private Securities Litigation Reform Act of 1995 (the "Act"). These statements are often, but not always, made through the use of words or phrases such as "believe," "will," "expect," "anticipate," "estimate," "intend," "plan," "forecast," "could," and "would." Examples of such forward looking statements include statements regarding the timing, design, scope, and anticipated results of our clinical development of MCT-475. MultiCell bases these forward-looking statements on current expectations about future events. They involve known and unknown risks, uncertainties and assumptions that may cause actual results, levels of activity, performance or achievements to differ materially from those expressed or implied by any forward-looking statement. Some of the risks, uncertainties and assumptions that could cause actual results to differ materially from estimates or projections in the forward-looking statement include, but are not limited to, the risk that we might not achieve our anticipated clinical development milestones, receive regulatory approval, or successfully commercialize MCT-475 as expected, the market for our products will not grow as expected, and the risk that our products will not achieve expectations. For additional information about risks and uncertainties MultiCell faces, see documents MultiCell files with the SEC, including MultiCell's report on Form 10-KSB for the fiscal year ended November 30, 2005, and all our quarterly and other periodic SEC filings. MultiCell claims the protection of the safe harbor for forward-looking statements under the Act and each assume no obligation and expressly disclaim any duty to update any forward-looking statement to reflect events or circumstances after the date of this news release or to reflect the occurrence of subsequent events.
SOURCE: MultiCell Technologies, Inc.
MultiCell Technologies, Inc. Dr. Stephen Chang, CEO 401-333-0610 MCETInvestor@MultiCelltech.com Copyright Business Wire 2007 End of Story
MCT-475 Targets Multibillion Dollar Worldwide Market for the Treatment of Colorectal Cancer, A Leading Cause of Death Among Cancer Patients
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Last Update: 3:30 AM ET Feb 15, 2007
SAN DIEGO, Feb 15, 2007 (BUSINESS WIRE) -- MultiCell Technologies, Inc. (MCET :
multicell technologies inc com new
News , chart, profile, more
Last: 0.200.000.00%
12:24am 02/15/2007
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Sponsored by:
MCET0.20, 0.00, 0.0% ) , developing first-in-class drugs based on advanced immune system modulation technologies, announced today it has reached a developmental milestone to advance its colorectal cancer lead therapeutic candidate to preclinical development status. MCT-475 is indicated as a prospective treatment for metastatic colorectal cancer, the third leading cause of death among both men and women in the United States. MCT-475 is a patent pending antigen-presenting immunoglobulin therapeutic which is intended to be co-administered with MCT-465, a Toll-like Receptor (TLR) agonist.
"Previously we demonstrated that co-administration of MCT-465 with our patent pending antigen-presenting immunoglobulin therapeutic IgNP prototype completely destroyed tumors, and prevented mortality and recurrence in animal models," said Dr. Stephen Chang, President and CEO of Multicell Technologies. "MCT-475 is designed to activate the adaptive immune system to target unique structural motifs located on the surface of human metastatic colorectal cancer cells, while MCT-465 is designed to activate the innate immune system through TLR signaling. Working together, MCT-475 and MCT-465 stimulate the body's immune system to target and kill metastatic colorectal cells."
Colorectal cancer is the third most common cancer in both men and women in the United States, and remains the third leading cause of death from cancer in the United States. The American Cancer Society estimates that about 145,000 new cases of colorectal cancer were reported in 2005.
According to the World Health Organization's April 2003 report on global cancer rates more than 940,000 new cases of colorectal cancer, and nearly 500,000 deaths are reported worldwide each year. The overall 5-year survival rate from the various types of colorectal cancer is approximately 60%, whereas for metastatic colorectal cancer, the 5-year survival rate is about 5%.
Risk factors for metastatic cancer include age, a diet rich in fat and cholesterol, inflammatory bowel disease, and genetic predisposition. If detected early, colorectal cancer is curable by surgery. Chemotherapy can prolong survival in patients where the disease has metastasized and reached the lymph nodes.
MultiCell is an innovator in the science of modulating the human immune system with unique platform technologies, focusing on the development of breakthrough drugs to treat serious diseases, including multiple sclerosis, type-1 diabetes, influenza, and cancer.
About MultiCell Technologies, Inc.
MultiCell Technologies, Inc. is an integrated biopharmaceutical company committed to the development of breakthrough therapeutics based on a portfolio of therapeutic candidates and patented drug development technology. MultiCell's drug development program is focused on modulation of the immune system.
MultiCell's therapeutic pipeline includes drug candidates some of which are in various advanced stages of human clinical trials. These therapies include:
-- MCT-125 for the treatment of chronic fatigue in MS patients.
-- MCT-175 for the treatment of relapsing-remitting MS.
-- MCT-275 for the treatment of type-1 diabetes.
-- MCT-465 an adjuvant therapy for the treatment of virus infection and cancer.
-- MCT-475 for the treatment of colorectal cancer.
The Company also holds unique cell-based technology for use in drug discovery screening applications, and is a leading producer of the cell lines needed by the biotechnology industry to develop new drugs. For more information about MultiCell Technologies, please visit http://www.multicelltech.com.
Caution Regarding Forward-Looking Statements
Any statements in this press release about MultiCell's expectations, beliefs, plans, objectives, assumptions or future events or performance are not historical facts and are forward-looking statements for purposes of the Private Securities Litigation Reform Act of 1995 (the "Act"). These statements are often, but not always, made through the use of words or phrases such as "believe," "will," "expect," "anticipate," "estimate," "intend," "plan," "forecast," "could," and "would." Examples of such forward looking statements include statements regarding the timing, design, scope, and anticipated results of our clinical development of MCT-475. MultiCell bases these forward-looking statements on current expectations about future events. They involve known and unknown risks, uncertainties and assumptions that may cause actual results, levels of activity, performance or achievements to differ materially from those expressed or implied by any forward-looking statement. Some of the risks, uncertainties and assumptions that could cause actual results to differ materially from estimates or projections in the forward-looking statement include, but are not limited to, the risk that we might not achieve our anticipated clinical development milestones, receive regulatory approval, or successfully commercialize MCT-475 as expected, the market for our products will not grow as expected, and the risk that our products will not achieve expectations. For additional information about risks and uncertainties MultiCell faces, see documents MultiCell files with the SEC, including MultiCell's report on Form 10-KSB for the fiscal year ended November 30, 2005, and all our quarterly and other periodic SEC filings. MultiCell claims the protection of the safe harbor for forward-looking statements under the Act and each assume no obligation and expressly disclaim any duty to update any forward-looking statement to reflect events or circumstances after the date of this news release or to reflect the occurrence of subsequent events.
SOURCE: MultiCell Technologies, Inc.
MultiCell Technologies, Inc. Dr. Stephen Chang, CEO 401-333-0610 MCETInvestor@MultiCelltech.com Copyright Business Wire 2007 End of Story
auf zum ONE DOLLAR
Antwort auf Beitrag Nr.: 28.960.409 von BIOMIRA am 23.04.07 21:25:29und ...?
Hallo Freunde,
heute ist Kaufsignal!
Einstieg nicht verpassen!
Herzliche Grüße und gute Nacht!
diegutefee
heute ist Kaufsignal!
Einstieg nicht verpassen!
Herzliche Grüße und gute Nacht!
diegutefee
sehe ich auch so
CDCI
MODC
PHEI
alles extrem ausgebommt.
mk 200 tausen
umsatz 9 mio
das ding explodiert bei der nächsten news
CDCI
MODC
PHEI
alles extrem ausgebommt.
mk 200 tausen
umsatz 9 mio
das ding explodiert bei der nächsten news
Hallo Freunde,
wer nicht kauft, ist selber schuld!
Herzliche Grüße
diegutefee
P.S.:
Nicht jeder hat eine Trüffelnase!
wer nicht kauft, ist selber schuld!
Herzliche Grüße
diegutefee
P.S.:
Nicht jeder hat eine Trüffelnase!
=)
LOL 750.000
hoffe ihr beiden habt alle rausgehauen heut.
hoffe ihr beiden habt alle rausgehauen heut.
Antwort auf Beitrag Nr.: 31.927.382 von diegutefee am 10.10.07 16:50:10 habe gestern gekauft schnäppchen
Antwort auf Beitrag Nr.: 31.950.379 von Joe_Trader am 12.10.07 09:26:35habt ihr den trade gesehen ????
0.108 391000 OBB 15:32:35
0.108 391000 OBB 15:32:35
Antwort auf Beitrag Nr.: 31.950.888 von Joe_Trader am 12.10.07 09:59:19
Die NEWS war super, vielleicht geht es heute wieder nach oben !
Die NEWS war super, vielleicht geht es heute wieder nach oben !
Antwort auf Beitrag Nr.: 31.951.335 von kirroyal am 12.10.07 10:25:35z.Z. nicht
Hallo Freunde,
meine Adleraugen haben alles gesehen!
Die Manipulation nach unten ist ja offensichtlich!
Ab 0,07 $ intraday reverse!
Ich habe jedenfalls nichts verkauft!
Herzliche Grüße und schönes Wochenende!
diegutefee
meine Adleraugen haben alles gesehen!
Die Manipulation nach unten ist ja offensichtlich!
Ab 0,07 $ intraday reverse!
Ich habe jedenfalls nichts verkauft!
Herzliche Grüße und schönes Wochenende!
diegutefee
Antwort auf Beitrag Nr.: 31.962.049 von diegutefee am 12.10.07 20:18:08weißt du ob mct 125 das am weitteste entwickelte product ist ??
wann ist die Phase 2B beendet ??
wann ist die Phase 2B beendet ??
Antwort auf Beitrag Nr.: 31.962.049 von diegutefee am 12.10.07 20:18:08habe gestern meine posi verdoppelt
denke es genug kohle gefloßen sein
die nächsten q zahlen sollte den deal doch beinhalten,oder ??
die nächsten q zahlen sollte den deal doch beinhalten,oder ??
jemand was nrurs zu dem Artikel gelesen???
---------------------------
MCT-125 in der klinischen Erprobung gegen MS-bedingte Fatigue
25.10.06 | Die Firma Multicell Technologies Inc. teilt mit, dass in England eine klinische Phase IIb-Studie mit der Substanz MCT-125 bei MS-bedingter Fatigue starten soll.
Fatigue (abnorme Ermüdbarkeit bzw. Müdigkeit) ist eines der häufigsten Symptome der Multiplen Sklerose. Es gibt kein Medikament, das zu Behandlung der Fatigue zugelassen ist. In vorangegangenen klinischen Studien hatte die Substanz gute Erfolge gezeigt.
Quelle: Reuters
---------------------------
---------------------------
MCT-125 in der klinischen Erprobung gegen MS-bedingte Fatigue
25.10.06 | Die Firma Multicell Technologies Inc. teilt mit, dass in England eine klinische Phase IIb-Studie mit der Substanz MCT-125 bei MS-bedingter Fatigue starten soll.
Fatigue (abnorme Ermüdbarkeit bzw. Müdigkeit) ist eines der häufigsten Symptome der Multiplen Sklerose. Es gibt kein Medikament, das zu Behandlung der Fatigue zugelassen ist. In vorangegangenen klinischen Studien hatte die Substanz gute Erfolge gezeigt.
Quelle: Reuters
---------------------------
Hallo Joe Trader,
Hemispherx und MCET "laufen um die Wette"!
MCET ist jedenfalls mit der Forschung und Entwicklung
schon ziemlich weit!
Hemispherx hat auch ein sehr gutes Produkt in der Pipeline!
Deshalb habe ich beide Werte im Depot!
Herzliche Grüße und schönen Abend!
diegutefee
Hemispherx und MCET "laufen um die Wette"!
MCET ist jedenfalls mit der Forschung und Entwicklung
schon ziemlich weit!
Hemispherx hat auch ein sehr gutes Produkt in der Pipeline!
Deshalb habe ich beide Werte im Depot!
Herzliche Grüße und schönen Abend!
diegutefee
Hallo Freunde,
zur Info:
Ich kaufe heute wieder nach!
Es besteht kein Grund, weshalb man verkaufen sollte!
Herzliche Grüße
diegutefee
zur Info:
Ich kaufe heute wieder nach!
Es besteht kein Grund, weshalb man verkaufen sollte!
Herzliche Grüße
diegutefee
Antwort auf Beitrag Nr.: 32.294.106 von diegutefee am 05.11.07 16:57:27überlege gerade bei 0,032 $ zu kaufen .
sollte eigtlich mal wieder hoch gehen.
sollte eigtlich mal wieder hoch gehen.
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