Recce Pharmaceuticals Reports Positive Preclinical Data of RECCE 327 in Lung Infection Pilot Study - Seite 2

Ventilator-associated pneumonia (VAP) is a major concern in healthcare settings, occurring in 9-27% of mechanically ventilated patients.⁴ Given the high incidence and severity of VAP, R327’s results suggest it could fill a critical gap in the treatment of VAP or similar infections​. Hospital-acquired pneumonia (HAP), one of the most common nosocomial infections, is associated with significant clinical and economic burdens, such as long-term hospitalization, high medical costs, and increased morbidity and mortality.⁵

About Recce Pharmaceuticals Ltd
Recce Pharmaceuticals Ltd (ASX: RCE, FSE: R9Q) is developing a New Class of Synthetic Anti-Infectives designed to address the urgent global health problems of antibiotic-resistant superbugs and emerging viral pathogens.

Recce’s anti-infective pipeline includes three patented, broad-spectrum, synthetic polymer anti-infectives: RECCE 327 (R327) as an intravenous and topical therapy that is being developed for the treatment of serious and potentially life-threatening infections due to Gram-positive and Gram-negative bacteria, including their superbug forms; RECCE 435 (R435) as an orally administered therapy for bacterial infections; and RECCE 529 (R529) for viral infections. Through their multi-layered mechanisms of action, Recce’s anti-infectives have the potential to overcome the processes utilised by bacteria and viruses to overcome resistance – a current challenge facing existing antibiotics.

The World Health Organization (WHO) added R327, R435, and R529 to its list of antibacterial products in clinical development for priority pathogens, recognising Recce’s efforts to combat antimicrobial resistance. The FDA granted R327 Qualified Infectious Disease Product designation under the Generating Antibiotic Initiatives Now (GAIN) Act, providing Fast Track Designation and 10 years of market exclusivity post approval. R327 is also included on The Pew Charitable Trusts’ Global New Antibiotics in Development Pipeline as the sole synthetic polymer and sepsis drug candidate in development.

Recce wholly owns its automated manufacturing, supporting current clinical trials. Recce’s anti-infective pipeline aims to address synergistic, unmet medical needs by leveraging its unique technologies.

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