IMM.L (MKap $85 M) Multiple Blockbuster Kandidat kurz vor final P3 Daten (1Q 2018) - Älteste Beiträge zuerst (Seite 112)

[Twohybrid]

Sorry, die Tabellen hat es beim Copy&Paste zerschlagen:


26 SEPTEMBER 2018

ImmuPharma PLC
("ImmuPharma" or the "Company")

INTERIM RESULTS ANNOUNCEMENT
for the six months ended 30 June 2018

ImmuPharma PLC (LSE:IMM), ("ImmuPharma" or the "Company"), the specialist drug discovery and development company, is pleased to announce its interim results for the six months ended 30 June 2018 (the "Period").

Key Highlights

LupuzorTM

•Lupuzor™ demonstrated a superior response rate over placebo (52.5% vs 44.6% "responders") in the primary analysis on the Full Analysis Set of all 202 patients. However, due to the high response rate in the placebo group, this superior response did not allow statistical significance to be reached (p = 0.2631) and the trial's primary end point was not met.

•Across the whole study population, in those patients who had anti-dsDNA autoantibodies, LupuzorTM demonstrated a superior response rate over placebo (61.5% vs 47.3%, p = 0.0967). Although these results were not statistically significant, further data analysis demonstrated that in the Europe cohort (130 patients) LupuzorTM plus standard of care showed statistically significant reductions in disease activity compared to placebo plus standard of care in 79 patients who were anti-dsDNA autoantibody positive (71.1% vs 48.8%, p = 0.0218).

•The study confirmed the outstanding safety profile of LupuzorTM, with no serious adverse events reported.

•As announced on 7 September 2018, agreement signed with a specialist provider to enter LupuzorTM into a 'Managed Access Programme'.

•Open label extension study completes recruitment.


Other programs

•Nucant (cancer) program - Clinical Development Collaboration with Incanthera Limited.

•Peptide platform program / Ureka subsidiary - ImmuPharma to begin divestment process.

Financial Position

•£10 million fundraising (before expenses) successfully completed in January 2018.

•Stable financial performance over the Period, in line with market expectations
o Net assets of £9.9 million (31 December 2017: £3.6 million)
o Loss for the period of £4.1 million (H1 2017: £3.0 million)
Research and Development expenses of £2.5 million (H1 2017: £2.3 million)
o Basic and diluted loss per share of 2.94p (H1 2017: 2.34p)

Appointment of new joint brokers

•Stanford Capital Partners and SI Capital appointed as joint brokers, working in conjunction with current NOMAD and broker, Northland Capital Partners.

Commenting on the Interims and outlook Tim McCarthy, Chairman, said:

"The Board is pleased to announce the interim results for the six months ended 30 June 2018. It has been a busy period for the Board following the announcement of the Phase III trial results for Lupuzor in April 2018. We remain focused on delivering a business strategy which provides the optimum route forward for ImmuPharma and its shareholders, based on its current assets, resources and knowhow. We were obviously disappointed with the outcome of the Phase III trial results but are excited to be progressing the Managed Access Programme with a new strategic partner, which allows lupus patients early access to LupuzorTM. In the medium term, we remain focussed on achieving the full regulatory approval of LupuzorTM which we believe has the potential to be a ground breaking drug for lupus patients with blockbuster potential in commercial terms.

Our Nucant programme and Ureka subsidiary have been part of our portfolio for a number of years. We are equally excited by the potential of both. We believe the strategy we announced earlier this month, together with a robust financial position, will create enhanced value for shareholders going forward."

This announcement contains inside information for the purposes of Article 7 of Regulation (EU) 596/2014. ("MAR")


For further information please contact:
ImmuPharma PLC + 44 (0) 20 7152 4080
Tim McCarthy, Chairman
Dimitri Dimitriou, Chief Executive Officer
Tracy Weimar, Vice President, Operations and Finance
Lisa Baderoon, Head of Investor Relations + 44 (0) 7721 413496

Northland Capital Partners Limited, Nomad & Joint Broker [phone]
David Hignell, Jamie Spotswood, Dugald Carlean, Corporate Finance
Rob Rees, Corporate Broking

Stanford Capital Partners, Joint Broker
Patrick Claridge
Chris Coleman
[phone]
SI Capital, Joint Broker
Nick Emerson [phone]


CHAIRMAN'S STATEMENT

INTERIM HIGHLIGHTS

The first half of 2018 saw the completion of our pivotal Phase III trial for LupuzorTM, our candidate for the treatment of lupus. Top-line results were announced on 17 April 2018 with further analysis provided on 29 May 2018. Following these results, ImmuPharma has recently signed an agreement with a specialist provider to distribute LupuzorTM via a Managed Access Programme. This will allow lupus patients early access to LupuzorTM prior to any regulatory filing.

ImmuPharma has, on 6 September 2018, signed a Heads of Terms on a clinical development collaboration for the Nucant cancer programme with Incanthera Limited, a specialist oncology development company. Further, following an extensive review, it has been decided that the Company's Ureka subsidiary which focuses on peptide treatments for metabolic disorders is not part of the ongoing strategy of ImmuPharma which is now fully focused on utilising its resources to develop late stage assets. Consequently, we are beginning the process of divesting Ureka.

In other developments, we were pleased to have completed a successful fund raising of £10 million (before expenses) in January 2018. The fund raising was supported by long term shareholders and the addition of new institutional and private investors.

LupuzorTM Phase III results and next steps

The Phase III trial was a double-blind, randomised, placebo-controlled trial. The study involved patients being dosed for one year, receiving 0.2mg once per month subcutaneously. 293 patients were screened illustrating the demand from physicians for a new, safe and effective treatment for lupus. Of these, the required 202 patients were successfully recruited and randomised (dosed). Patients participated in the trial in 7 countries across 28 sites.

The clinical trial was undertaken primarily by Simbec-Orion, an international clinical research organisation, who specialises in rare and orphan conditions and has previous direct experience in lupus trials. This was a pivotal study designed to demonstrate the safety and efficacy of Lupuzor™.

Lupuzor™ demonstrated a superior response rate over placebo (52.5% vs 44.6% "responders") in the primary analysis on the Full Analysis Set of all 202 patients. However, due to the high response rate in the placebo group, this superior response did not allow statistical significance to be reached (p = 0.2631) and the trial's primary end point was not met.

Across the whole study population, in those patients who had anti-dsDNA autoantibodies, LupuzorTM demonstrated a superior response rate over placebo (61.5% vs 47.3%, p = 0.0967). Although these results were not statistically significant, further data analysis demonstrated that in the Europe cohort (130 patients) LupuzorTM plus standard of care showed statistically significant reductions in disease activity compared to placebo plus standard of care in 79 patients who were anti-dsDNA autoantibody positive (71.1% vs 48.8%, p = 0.0218).

The study confirmed the outstanding safety profile of LupuzorTM, with no serious adverse events reported.

Scientific literature indicates that approximately 60% - 70% of patients diagnosed for lupus are anti-dsDNA autoantibody positive. These proportions were seen in the Europe cohort (60.8% of patients) and could therefore be considered as representative of the overall lupus population.

In those patients who were anti-dsDNA autoantibody negative, there was almost no difference in disease activity reduction between the active group and the comparator group. Anti-dsDNA autoantibodies are a recognised biomarker for Systemic Lupus Erythematosus.

This finding indicates that the activity of LupuzorTM could be correlated with the presence of anti-dsDNA autoantibodies in lupus patients. ImmuPharma believes that predictive biomarkers, such as anti-dsDNA autoantibodies, could allow identification of patients that are more likely to respond positively to treatment with LupuzorTM.

LupuzorTM next steps - Managed Access Program

ImmuPharma is planning to move forward with a Managed Access Program for LupuzorTM. Recognising that lupus is a disease with significant unmet medical need and given the advanced level of clinical trial investigation completed, ImmuPharma would like to meet demand for access to LupuzorTM by lupus patients who, together with their physicians, request it.

Extension study

The LupuzorTM extension study, which was announced on 18 January 2018, is continuing and recruitment is now complete with a total of 62 patients eligible from the original Phase III trial. We believe that this will provide more valuable information on the potential efficacy and safety of LupuzorTM. The study is anticipated to report results in Q2 2019.

Nucant Platform

A number of options have been under review to develop the Company's Nucant cancer programme, which has demonstrated promising results in two Phase I trials (safety and dose-finding studies).

In order to progress the programme, on 6 September 2018 ImmuPharma signed Heads of Terms on a clinical development collaboration for the Nucant cancer programme, with Incanthera Limited ("Incanthera"), a specialist oncology development company.

Key highlights of the Heads of Terms are summarised below:

•Incanthera, based on its positive due-diligence on the Company's Nucant technology, will license in and take up the continued clinical development of the Nucant cancer programme as an integral part of its own cancer development portfolio.
•As an integral part of the collaboration, upon signing the Heads of Terms, ImmuPharma has invested £2m into Incanthera by subscribing for 363,637 new ordinary Incanthera shares at a price of £5.50 per share. This investment values Incanthera at a pre-money valuation of approximately £10m and is consistent with the most recent funding round that Incanthera completed in March 2018. Following this investment, ImmuPharma will have a circa 16% shareholding in Incanthera.
•ImmuPharma has granted Incanthera a period of exclusivity until 31 December 2018, during which the Company and Incanthera will finalise the terms of a Definitive Licence Agreement for the Nucant technology. These terms are expected to include, but will not be limited to the following:
o Incanthera will pay a licence payment to ImmuPharma of £1 million, with this payment to be made via the issuance of new ordinary shares in Incanthera. This payment in shares is separate and will be in addition to the shareholding which Immupharma currently holds as described above;
o Incanthera will be responsible for all of the development costs for the Nucant programme; and,
o All future commercialisation revenues will be shared equally between the two companies.
Ureka - Divestment process

Ureka, ImmuPharma's wholly owned subsidiary, based in Bordeaux, which is carrying out research into treatments for Type II diabetes and NASH (Non-Alcoholic-Steato-Hepatitis) has recently demonstrated success in recognised preclinical studies.

Following an extensive review by ImmuPharma's Board of directors, it has been decided that Ureka, whilst having exciting and innovative technologies, is not part of the ongoing strategy of ImmuPharma, which is now fully focused on utilising its resources to develop late stage assets.

As such, ImmuPharma, with its advisors, will now commence a process of considering all opportunities to divest Ureka. The intention is to allow ImmuPharma to divest Ureka, whilst still retaining an interest in any future commercial success.

Financial Review

ImmuPharma's cash balance at 30 June 2018 was £9.02 million (£2.73 million at 31 December 2017, £3.13 million at 30 June 2017). Basic and diluted loss per share were 2.94p and 2.94p respectively (30 June 2017: 2.34p and 2.34p). In line with the Company's current policy, no interim dividend is proposed.

Operating loss for the Period was £4.1 million (£3.2 million for the six months ended 30 June 2017). Research and development expenditure in the Period was £2.5 million (£2.3 million for the six months ended 30 June 2017) reflecting primarily the expenditure related to the LupuzorTM Phase III clinical trial. Administrative expenses were £1.0 million during the Period (£0.8 million for the six months ended 30 June 2017). The share based expense was £775k (£131k for the period ended 30 June 2017) which includes a reduction for the National Insurance provision which was nil due to the decrease in share price from 31 December 2017 to 30 June 2018.

Given the stage of ImmuPharma's development, the fact that losses have continued to be made is to be expected since there is minimal revenue and business activity is concerned with significant investment in the form of clinical development expenditure, in addition to maintaining the infrastructure of the Company.

Current Activities and Outlook

The Board has been focused on delivering a business strategy which provides the optimum route forward for ImmuPharma and its shareholders, based on its current assets, resources and knowhow. We are excited to be progressing the Managed Access Programme which allows lupus patients early access to LupuzorTM. In the medium term, we remain focussed on achieving the full regulatory approval of LupuzorTM which we believe has the potential to be a ground breaking drug for lupus patients with blockbuster potential in commercial terms.

Our Nucant programme and Ureka subsidiary have been part of our portfolio for a number of years. We are equally excited by the potential of both. We believe the strategy we are pursuing with the collaboration with Incanthera Limited for the Nucant and for divestment of Ureka will create enhance value for shareholders going forward.

The Board would like to thank its shareholders, both longstanding and those who participated in the January 2018 fundraising, for their support as well as its staff, corporate and scientific advisers including Simbec-Orion and the CNRS (Centre Nationale de la Recherche Scientifique) for their continued collaboration.

Tim McCarthy
Chairman

ImmuPharma PLC

CONSOLIDATED INCOME STATEMENT
FOR THE PERIOD ENDED 30 JUNE 2018




Note Unaudited
6 months ended
30 June 2018 Audited
Year
ended 31 December
2017 Unaudited
6 months ended
30 June 2017
£ £ £
Continuing operations
Revenue 1 73,392 150,462 86,504
Research and development expenses (2,455,490) (5,121,388) (2,345,815)
Administrative expenses (992,085) (1,520,356) (796,403)
Share based expense (775,135) (742,752) (131,237)

Operating loss (4,149,318) (7,234,034) (3,186,951)

Finance costs (29,425) (3,858) (375)
Finance income 6,077 240,447 153,915


Loss before taxation (4,172,666) (6,997,445) (3,033,411)

Tax 110,237 774,244 (485)


Loss for the period (4,062,429) (6,223,201) (3,033,896)


Attributable to:
Equity holders of the parent company (4,062,429) (6,223,201) (3,033,896)


Loss per ordinary share

Basic and diluted 2 (2.94)p (4.75)p (2.34)p




ImmuPharma PLC

CONSOLIDATED STATEMENT OF COMPREHENSIVE INCOME
FOR THE PERIOD ENDED 30 JUNE 2018


Unaudited
6 months ended
30 June
2018 Audited
Year
ended 31 December
2017 Unaudited
6 months ended
30 June
2017
£ £ £

Loss for the financial period (4,062,429) (6,223,201) (3,033,896)


Other comprehensive income
Items that may be reclassified subsequently to profit or loss:

Exchange differences on translation of foreign operations
29,459
(91,568)
(56,133)


Total items that may be reclassified subsequently to profit or loss 29,459 (91,568) (56,133)

Other comprehensive loss for the period
29,459
(91,568)
(56,133)


Total comprehensive loss for the period (4,032,970) (6,314,769) (3,090,029)



ImmuPharma PLC

CONSOLIDATED STATEMENT OF FINANCIAL POSITION
AS AT 30 JUNE 2018

Note Unaudited
30 June
2018 Audited
31 December
2017 Unaudited
30 June 2017
£ £ £
Non-current assets
Intangible assets 481,667 482,268 497,585
Property, plant and equipment 120,675 161,399 192,573


Total non-current assets 602,342 643,667 690,158


Current assets
Trade and other receivables 1,174,720 1,644,128 2,439,143
Derivative financial asset - - 943,861
Cash and cash equivalents 9,015,630 2,729,468 3,131,595


Total current assets 10,190,350 4,373,596 6,514,599


Current liabilities
Financial liabilities - borrowings 138,214 142,393 119,430
Trade and other payables 737,035 929,569 473,867
Provisions - 57,517 33,162


Total current liabilities 875,249 1,129,479 626,459


Net current assets 9,315,101 3,244,117 5,888,140


Non-current liabilities
Financial liabilities - borrowings 61,209 117,297 170,232
Provisions - 195,989 -


Net assets 9,856,234 3,574,498 6,480,066


EQUITY
Ordinary shares 13,946,744 13,252,299 13,252,298
Share premium 27,320,143 18,728,519 18,728,519
Merger reserve 106,148 106,148 106,148
Other reserves (1,902,921) (2,961,017) (3,316,753)
Retained earnings (29,613,880) (25,551,451) (22,362,146)


Total equity 9,856,234 3,574,498 6,408,066


ImmuPharma PLC
CONSOLIDATED STATEMENT OF CHANGES IN EQUITY
FOR THE PERIOD ENDED 30 JUNE 2018
Share capital Share premium
Merger
reserve Other reserves -
Acquisition
reserve Other reserves -
Translation
Reserve Other reserves -
Equity shares
to be issued

Retained
Earnings Total
equity
£ £ £ £ £ £ £ £
At 1 January 2017
12,463,836 15,678,054 106,148 (3,541,203) (1,609.673) 1,777,131 (19.328.250) 5,546,043
Loss for the financial period - - - - - - (3,033,896) (3,033,896)
Exchange differences on translation
of foreign operations - - - - (56,133) - - (56,133)
New issue of equity capital 788,462 3,311,542 - - - - - 4,100,004
Cost of new issue of equity capital - (261,077) - - - - - (261,077)
Share based payments - - - - - 113,125 - 113,125

At 30 June 2017 13,252,298 18,728,519 106,148 (3,541,203) (1,665,806) 1,890,256 (22,362,146) 6,408,066

At 1 January 2017 12,463,836 15,678,054 106,148 (3,541,203) (1,609,673) 1,777,131 (19,328,250) 5,546,043

Loss for the financial year - - - - - - (6,223,201) (6,223,201)
Exchange differences on translation
of foreign operations - - - - (91,568) - - (91,568)
New issue of equity capital 788,463 3,311,542 - - - - - 4,100,005
Cost of new issue of equity capital - (261,077) - - - - - (261,077)
Share based payments - - - - - 504,296 - 504,296

At 31 December 2017 & 1 January 2018 13,252,299 18,728,519 106,148 (3,541,203) (1,701,241) 2,281,427 (25,551,451) 3,574,498

Loss for the financial period - - - - - - (4,062,429) (4,062,429)
Exchange differences on translation
of foreign operations - - - - 29,459 - - 29,459
New issue of equity capital 694,445 9,305,555 - - - - - 10,000,000
Cost of new issue of equity capital - (713,931) - - - - - (713,931)
Share based payments - - - - - 1,028,637 - 1,028,637

At 30 June 2018 13,946,744 27,320,143 106,148 (3,541,203) (1,671,782) 3,310,064 (29,613,880) 9,856,234
Attributable to:-

Equity holders of the parent company 13,946,744 27,320,143 106,148 (3,541,203) (1,671,782) 3,310,064 (29,613,880) 9,856,234



ImmuPharma PLC

CONSOLIDATED STATEMENT OF CASHFLOWS
FOR THE PERIOD ENDED 30 JUNE 2018

Note Unaudited
6 months ended
30 June 2018 Audited
Year
ended
31 December
2017 Unaudited
6 months ended
30 June
2017
£ £ £
Cash flows from operating activities
Cash used in operations 3 (3,150,500) (5,439,079) (3,200,329)
Tax 213,724 1,021,915 6,680
Interest paid (2,423) (3,858) (375)


Net cash used in operating activities (2,939,199)
(4,421,022) (3,194,024)


Investing activities
Purchase of property, plant and equipment (7,946) (25,491) (1,595)
Interest received 6,077 772 170


Net cash used in investing activities (1,869) (24,719) (1,425)


Financing activities
(Decrease)/increase in bank overdraft (122) (290) (138)
Loan repayments (58,615) (114,386) (80,447)
Gross proceeds from issue of new share capital 10,000,000 4,100,005 4,100,004
Settlements from sharing agreement - 1,667,380 682,360
Share capital issue costs (713,931) (261,077) (261,077)


Net cash generated from financing activities 9,227,332 5,391,632 4,440,702


Net increase in cash and cash equivalents
6,286,264 945,891 1,245,253
Cash and cash equivalents at start of period 2,729,468 1,876,718 1,876,718

Effects of exchange rates on cash and
cash equivalents
(102)
(93,141)
9,624



Cash and cash equivalents at end of period
9,015,630 2,729,468
3,131,595





ImmuPharma PLC

NOTES TO THE CONSOLIDATED INTERIM ACCOUNTS FOR THE PERIOD ENDED 30 JUNE 2018

1 ACCOUNTING POLICIES

Basis of preparation

The interim financial information in this report has been prepared using accounting policies consistent with IFRS as adopted by the European Union. IFRS is subject to amendment and interpretation by the International Accounting Standards Board (IASB) and the IFRS Interpretations Committee and there is an ongoing process of review and endorsement by the European Commission. The financial information has been prepared on the basis of IFRS to be adopted by the European Union and applicable as at 31 December 2018. The Group has chosen not to adopt IAS 34 "Interim Financial Statements" in preparing the interim financial information.

The accounting policies applied are consistent with those that were applied to the financial statements for the year ending 31 December 2017, with the exception of IFRS 9 "Financial Instruments" and IFRS 15 "Revenue from Contracts with Customers" which are new standards applicable mandatory for the year ended 31 December 2018. These new standards will not have a material impact on the financial statements.

Non-Statutory accounts

The financial information set out in this interim report does not constitute the Group's statutory accounts, within the meaning of Section 434 of the Companies Act 2006. The statutory accounts for the year ended 31 December 2017 have been filed with Registrar of Companies. The auditors reported on those accounts; their report was unqualified, did not contain a statement under either Section 498 (2) or Section 498 (3) of the Companies Act 2006 and did not include references to any matters to which the auditor drew attention by way of emphasis. The financial information for the 6 months ended 30 June 2018 and 30 June 2017 is unaudited.

Copies of this statement will be available on the Company's website - www.immupharma.com.



2 LOSS PER SHARE


Unaudited
6 months ended 30 June 2018 Audited
Year ended 31 December
2017 Unaudited
6 months ended 30 June 2017
£ £ £

Loss
Loss for the purposes of basic and diluted loss per share being net loss attributable to equity shareholders (4,062,429)

(6,223,201) (3,033,896)


Number of shares
Weighted average number of ordinary shares for the purposes of basic loss per share 138,201,316 130,902,857 129,517,245



Basic loss per share (2.94)p (4.75)p


(2.34)p



Diluted loss per share (2.94)p (4.75)p (2.34)p



There is no difference between basic loss per share and diluted loss per share as the share options and warrants are anti-dilutive.

The ImmuPharma group has granted share options in respect of shares to be issued.



3 CASH USED IN OPERATIONS
Unaudited
6 months ended
30 June 2018 Audited
Year ended 31 December 2017 Unaudited
6 months
ended
30 June 2017
£ £ £

Operating loss (4,149,318) (7,234,034) (3,186,951)
Depreciation & amortisation 81,424 138,198 61,954
Share based payments 1,028,637 504,296 113,125
Decrease in trade & other receivables 358,921 643,466 34,004
(Decrease)/increase in trade & other payables (189,656) 143,378 (322,963)
(Decrease)/increase in provisions (253,506) 238,456 18,112
Gain/(loss) on foreign exchange (27,002) 127,161 82,390


Cash used in operations
(3,150,500)
(5,439,079)
(3,200,329)



4 SUBSEQUENT EVENTS


On 7 September 2018, ImmuPharma announced that a Heads of Terms agreement was signed with Incanthera Limited. Under the Heads of Terms agreement, Incanthera Limited will license in and take up the continued clinical development of the Nucant cancer programme as an integral part of its own cancer development portfolio. As part of the Heads of Terms, ImmuPharma has invested £2 million into Incanthera Limited by subscribing for 363,637 new ordinary Incanthera shares at a price of £5.50 per share. Following this investment, ImmuPharma will have approximately 16% shareholding in Incanthera Limited. Under the Heads of Terms, ImmuPharma has granted Incanthera Limited a period of exclusivity until 31 December 2018, during which the two companies will finalise terms of a Definitive License Agreement for the Nucant technology. These terms are expected to include, but will not be limited to Incanthera Limited paying a license payment to ImmuPharma of £1 million, with this payment being made via the issuance of new ordinary shares in Incanthera Limited. It is also planned to include confirmation that Incanthera Limited will be responsible for all of the development costs of the Nucant programme and confirmation that all future commercialisation revenues will be shared equally between the two companies.









This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact [e-mail] or visit www.rns.com.

END

[backonplastic]

Lupuzor wird immer mehr gebraucht ...

https://www.fiercebiotech.com/biotech/xencor-s-lead-lupus-an…

[bio-profi]

Dem Kurs hilft das Leider nicht. Fast allzeittief bei 12 !😡😡😡😡😡

[bio-profi]

Wenn jetzt genug Patienten sich bei der 500 Program regestrieren und falls die Nachzügler von der Phase 3 gute erbenisse vermelden, geht es wieder hoch. Die nächste news wird suf jedenfall positiv ausfallen. Glaube tiefer wird es nicht gehen!!

IMM.L (MKap $85 M) Multiple Blockbuster Kandidat kurz vor final P3 Daten (1Q 2018) | wallstreet-online.de - Vollständige Diskussion unter:
https://www.wallstreet-online.de/diskussion/1252583-1111-112…

[backonplastic]

Antwort auf Beitrag Nr.: 58.893.537 von bio-profi am 08.10.18 12:05:13

Na ja , die möglichen Alternativen schwinden immer mehr ! Ich glaube immu ist der einzige der es die letzten Jahre durch eine P3 geschafft hat. Mit zufriedenen Studienteilnehmern trotz Bürokratischen Fail der Studie.

[bio-profi]

Hallo,

Leider geht es hier nur in eine Richtung! Neues allzeit tief erreicht heute!?
Wie geht es hier weiter? Immer wenn ich denke der Boden ist erreicht, dann fällst sie nochmal! Leider kommen vom MM auch keine unterstützenden Maßnahmen!

Meinungen?

[aaahhh]

Antwort auf Beitrag Nr.: 58.927.104 von bio-profi am 11.10.18 10:19:07

Denke man muss abwarten was sich in den nächsten 2 Jahren ergibt, leider! Da kann immer mal was kommen, aber die Zeit wird es wohl brauchen und so wie es aussieht, sind da nicht alle bereit zu warten. Ist ja auch immer noch viel Risiko dabei. De Kurs wird ohne News vermutlich weiter nach geben. Weiter unten werden sich dann wohl wieder Einige trauen und die günstigen Kurse nutzen und auf eine Zulassung spekulieren. Aber das wird noch dauern. Außer irgendwer greift sich den Laden, kann auch immer noch passieren.
Gruß aaahhh

[bio-profi]

Kein Handel heute??
Ausgestetzt?
Übernahme?

[techinvestor69]

Antwort auf Beitrag Nr.: 58.941.270 von bio-profi am 12.10.18 11:54:28

Ist das Deine einzige Aktie oder hast Du hier zuviel Geld drin?

Du bist viel zu unentspannt...

[techinvestor69]

kam grad per E-Mail rein

ImmuPharma PLC

("ImmuPharma" or the "Company")

Nominated Adviser Status

ImmuPharma PLC (AIM: IMM.L), the specialist drug discovery and development company, announces that the Directors are aware of the proposed merger of its current nominated adviser ("NOMAD"), Northland Capital Partners ("Northland") with SP Angel Corporate Finance LLP. The Directors have also been informed that Northland has voluntarily agreed to relinquish its NOMAD status and will be removed from the register of NOMADs with effect from 7am (GMT) on 1 February 2019.

In accordance with AIM Rule 1, the Company is required to appoint a new NOMAD by 1 February 2019, if not, the Exchange will suspend trading in the Company's AIM Securities. If the Company does not appoint a replacement NOMAD by 4 March 2019, the admission of its AIM Securities will be cancelled.

The Company has commenced the process to appoint a new NOMAD and will make a further announcement in due course.

This announcement contains inside information for the purposes of Article 7 of Regulation (EU) No 596/2014 ("MAR").