SYNTA PHARMA.CORP mit STA-4783 - 500 Beiträge pro Seite

[Biotechspezialx]

Ein Investment das sich lohnen könnte.....


STA-4783 is the first drug in over 30 years to demonstrate an improvement in progression free survival in a double-blind, randomized, controlled, multi-center clinical trial in metastatic melanoma," said Dr. O'Day. "In a disease where there are so few treatment options for patients, it is vitally important to continue the development of new therapeutics such as STA-4783."

Dr. O'Day was the lead investigator on the Phase 2b trial of 81 patients with Stage IV melanoma, and will be the North American lead investigator for the Phase 3 trial of STA-4783. Synta has announced that it plans to initiate an international Phase 3 clinical trial to investigate STA-4783 as a first-line therapy for patients with metastatic melanoma in the third quarter of 2007.



STA-4783 is a novel, injectable, small molecule investigational drug candidate that induces a potent oxidative stress response in cancer cells, driving programmed cell death and enhancing the activity of anti-cancer agents that act through the mitochondrial apoptosis pathway, including paclitaxel. In November 2006, Synta received Fast Track designation from the FDA for the development of STA-4783 in metastatic melanoma.

Based on the broad-acting potential of its novel mechanism of action and the activity seen in laboratory experiments in other cancer types, Synta plans to investigate the use of STA-4783 in additional cancers and in combination with other agents, including announcing one or more Phase 2 studies in other cancer indications later in the year.

[Biotechspezialx]

Noch einmal heute Abend +11,69 % das Tempo nimmt rasant an Tempo nach oben zu!

So machen Biotechs Spaß...........