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29.11. 12:10
Millennium vor wichtiger Genehmigung
Millennium Pharmaceutical ist lt. CBO Holtzmann sehr optimistisch, daß ein neues Krebsmittel
namens Campath kurz vor der Genehmigung steht. Die Kommission wird am 14. Dezember
zusammentreten, eine Billigung des Medikaments werde bis Ende Februar 2001 erwartet.
Orbitx Fond Manager Bender bescheinigt dem Mittel ein großes Marktpotential mit zumindest $500
Mio. Umsatzpotential. Holtzmann erwähnte dies in einer Rede auf der Robertson Stephens Medical
Konferenz.
Millennium vor wichtiger Genehmigung
Millennium Pharmaceutical ist lt. CBO Holtzmann sehr optimistisch, daß ein neues Krebsmittel
namens Campath kurz vor der Genehmigung steht. Die Kommission wird am 14. Dezember
zusammentreten, eine Billigung des Medikaments werde bis Ende Februar 2001 erwartet.
Orbitx Fond Manager Bender bescheinigt dem Mittel ein großes Marktpotential mit zumindest $500
Mio. Umsatzpotential. Holtzmann erwähnte dies in einer Rede auf der Robertson Stephens Medical
Konferenz.
Dann schau Dir mal das hier an (Noch Fragen!!!!)
Like Corzine, Millennium Aims to Buy Its Way to the Top
By Dane Hamilton
Staff Reporter
11/30/00 11:56 AM ET
Who needs profits when you`re creating "the biopharmaceutical company of the future"?
That`s the Millennium (MLNM:Nasdaq - news) message these days. Some think the company is asking investors to take a lot on faith, considering its hefty $10.7 billion market cap.
The Run-up
Tracking Millennium`s rise
For one thing, Millennium`s drug development pipeline isn`t strong enough to carry the company to its goal of profits by 2004, according to Steve Holtzman, Millennium`s chief business officer. And while Holtzman said he anticipates that the Food and Drug Administration will approve Millennium`s first drug -- Campath, a leukemia treatment in development with Ilex Oncology (ILXO:Nasdaq - news) -- by early next year, neither that drug nor the seven or so earlier in the development maze is expected to be a big seller. Campath is due to be reviewed by an FDA advisory panel on Dec. 14.
Related Stories
For Biotech, This Time It`s Different
Q&A With Wasatch Funds` Robert Gardiner
Health Care`s Been the Big Winner, but Can You Assume the Risk?
So Millennium plans to acquire companies or products with its $1.45 billion cash pile in an effort to reach profitability by 2004, says Holtzman. "Our pipeline is too early, so we have an aggressive acquisition and in-licensing strategy," Holtzman said in an interview after speaking at the Robertson Stephens Medical Conference in New York this week.
That worries some investors who say the goal of profits is based on a lot of unknowns. "They could buy their way into profits," says Jim Fiore, who heads the Life Science Group, a Greenwich, Conn., biotech fund that holds some Millennium. But, says Fiore, "their market cap is high, and if they stumble, that`s going to get killed. Not stumbling in the next four years is going to be a pretty neat trick."
Mass Customization
Holtzman told investors not to expect profits in the near term as the company invests in what many believe is going to be the future of the drug industry: personalized medicines that are tailored to a specific genetic makeup.
While no drug has yet been developed along those lines, some have come close. For instance, Genentech`s (DNA:NYSE - news) breast cancer drug Herceptin is aimed at patients with certain genetic variations. Many more such drugs are in development.
Back to Earth?
Millennium`s bumpy 2000
Millennium, which has alliances to develop such drugs with more than a dozen companies including Aventis (AVE:NYSE - news), Bristol-Myers Squibb (BMY:NYSE - news), Pfizer (PFE:NYSE - news) and more, aims to be on the forefront of that risky endeavor. And it raised $767 million from investors in the last few months by touting those prospects.
"This year and for the next few years, we are going into an investment mode," Holtzman told a standing-room-only crowd at one of the nation`s top biotech investing forums. "Some people call it a loss."
In reaching to be the next-generation drug company, Millennium is bucking a trend that`s one of the key selling points for the risky biotech industry these days: the prospect of profits. Of the nation`s 400 or so publicly traded biotech companies, more than 30 could be profitable by next year, double what`s expected this year, analysts forecast.
Like Incyte (INCY:Nasdaq - news) and Celera (CRA:NYSE - news), both Millennium and Human Genome Sciences (HGSI:Nasdaq - news) were early movers into compiling giant genome databases for big pharmaceutical companies to use to find new drugs.
Then Millennium and HGS both eventually decided they also wanted to be drug rather than data companies, unlike their rivals, since drugs generate higher profits. But while both have drugs in their pipelines, most are still years from the market.
Such blue-sky prospects have been the subject of much debate among investors, as reflected in Millennium`s volatile stock price, which has swung from $20 to $90 in the last year. Thursday, the stock was off $1.69, or 3%, at $48.94 amid a sizable tech selloff. And market values for both Millennium and HGS are much higher than for other biotech companies with drugs either on the market or in late-stage development, such as Vertex (VRTX:Nasdaq - news), Genzyme (GENZ:Nasdaq - news), Gilead (GILD:Nasdaq - news) or Idec (IDPH:Nasdaq - news).
Front-Runners
Still, some give the company the benefit of the doubt, saying that if anyone can make drugs from genes, it will be Millennium and HGS, even though much remains to be proved. "The idea is to do the development on their own, rather than rely on alliances with pharma companies," says Matthew Murray, fund manager for Alliance Capital`s biotech fund.
But there`s a disparity among investors who say profits should trump a speculative future. Given the risk that genomics may not turn out the cornucopia of new drugs that many people are expecting, some say profit would be a more useful goal. And that`s going to require some M&A activity for Millennium.
While Millennium`s revenue is growing (it generated $183 million in 1999 and is forecast to bring in $210 million in 2000), the stock currently trades well above the average 29 times 2001 revenue for similar genomics companies, according to Prudential Vector, which rates the stock a hold.
"Given that it is unknown what products the company might acquire and what their future revenue-generating potential might be, we believe that there is sufficient risk to justify a hold rating," said analyst Rob Toth in a recent note to investors.
--------------------------------------------------------------------------------
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Read our conflicts and disclosure policy.
Order reprints of TSC articles. Top
--------------------------------------------------------------------------------
Research Now
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CRA HGSI MLNM
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Like Corzine, Millennium Aims to Buy Its Way to the Top
By Dane Hamilton
Staff Reporter
11/30/00 11:56 AM ET
Who needs profits when you`re creating "the biopharmaceutical company of the future"?
That`s the Millennium (MLNM:Nasdaq - news) message these days. Some think the company is asking investors to take a lot on faith, considering its hefty $10.7 billion market cap.
The Run-up
Tracking Millennium`s rise
For one thing, Millennium`s drug development pipeline isn`t strong enough to carry the company to its goal of profits by 2004, according to Steve Holtzman, Millennium`s chief business officer. And while Holtzman said he anticipates that the Food and Drug Administration will approve Millennium`s first drug -- Campath, a leukemia treatment in development with Ilex Oncology (ILXO:Nasdaq - news) -- by early next year, neither that drug nor the seven or so earlier in the development maze is expected to be a big seller. Campath is due to be reviewed by an FDA advisory panel on Dec. 14.
Related Stories
For Biotech, This Time It`s Different
Q&A With Wasatch Funds` Robert Gardiner
Health Care`s Been the Big Winner, but Can You Assume the Risk?
So Millennium plans to acquire companies or products with its $1.45 billion cash pile in an effort to reach profitability by 2004, says Holtzman. "Our pipeline is too early, so we have an aggressive acquisition and in-licensing strategy," Holtzman said in an interview after speaking at the Robertson Stephens Medical Conference in New York this week.
That worries some investors who say the goal of profits is based on a lot of unknowns. "They could buy their way into profits," says Jim Fiore, who heads the Life Science Group, a Greenwich, Conn., biotech fund that holds some Millennium. But, says Fiore, "their market cap is high, and if they stumble, that`s going to get killed. Not stumbling in the next four years is going to be a pretty neat trick."
Mass Customization
Holtzman told investors not to expect profits in the near term as the company invests in what many believe is going to be the future of the drug industry: personalized medicines that are tailored to a specific genetic makeup.
While no drug has yet been developed along those lines, some have come close. For instance, Genentech`s (DNA:NYSE - news) breast cancer drug Herceptin is aimed at patients with certain genetic variations. Many more such drugs are in development.
Back to Earth?
Millennium`s bumpy 2000
Millennium, which has alliances to develop such drugs with more than a dozen companies including Aventis (AVE:NYSE - news), Bristol-Myers Squibb (BMY:NYSE - news), Pfizer (PFE:NYSE - news) and more, aims to be on the forefront of that risky endeavor. And it raised $767 million from investors in the last few months by touting those prospects.
"This year and for the next few years, we are going into an investment mode," Holtzman told a standing-room-only crowd at one of the nation`s top biotech investing forums. "Some people call it a loss."
In reaching to be the next-generation drug company, Millennium is bucking a trend that`s one of the key selling points for the risky biotech industry these days: the prospect of profits. Of the nation`s 400 or so publicly traded biotech companies, more than 30 could be profitable by next year, double what`s expected this year, analysts forecast.
Like Incyte (INCY:Nasdaq - news) and Celera (CRA:NYSE - news), both Millennium and Human Genome Sciences (HGSI:Nasdaq - news) were early movers into compiling giant genome databases for big pharmaceutical companies to use to find new drugs.
Then Millennium and HGS both eventually decided they also wanted to be drug rather than data companies, unlike their rivals, since drugs generate higher profits. But while both have drugs in their pipelines, most are still years from the market.
Such blue-sky prospects have been the subject of much debate among investors, as reflected in Millennium`s volatile stock price, which has swung from $20 to $90 in the last year. Thursday, the stock was off $1.69, or 3%, at $48.94 amid a sizable tech selloff. And market values for both Millennium and HGS are much higher than for other biotech companies with drugs either on the market or in late-stage development, such as Vertex (VRTX:Nasdaq - news), Genzyme (GENZ:Nasdaq - news), Gilead (GILD:Nasdaq - news) or Idec (IDPH:Nasdaq - news).
Front-Runners
Still, some give the company the benefit of the doubt, saying that if anyone can make drugs from genes, it will be Millennium and HGS, even though much remains to be proved. "The idea is to do the development on their own, rather than rely on alliances with pharma companies," says Matthew Murray, fund manager for Alliance Capital`s biotech fund.
But there`s a disparity among investors who say profits should trump a speculative future. Given the risk that genomics may not turn out the cornucopia of new drugs that many people are expecting, some say profit would be a more useful goal. And that`s going to require some M&A activity for Millennium.
While Millennium`s revenue is growing (it generated $183 million in 1999 and is forecast to bring in $210 million in 2000), the stock currently trades well above the average 29 times 2001 revenue for similar genomics companies, according to Prudential Vector, which rates the stock a hold.
"Given that it is unknown what products the company might acquire and what their future revenue-generating potential might be, we believe that there is sufficient risk to justify a hold rating," said analyst Rob Toth in a recent note to investors.
--------------------------------------------------------------------------------
Send letters to the editor to letters@thestreet.com.
Read our conflicts and disclosure policy.
Order reprints of TSC articles. Top
--------------------------------------------------------------------------------
Research Now
on DLJdirect
CRA HGSI MLNM
Visit the DLJdirect Research Center
RELATED STORIES
Biotech/Pharmaceuticals
Glaxo Pulls Promising Bowel Drug After Side Effects
11/28/00 2:30 PM ET
The FDA asks the British drug giant to withdraw the lucrative treatment after patient deaths.
Biotech/Pharmaceuticals
Motorola, Compugen In DNA Chip Venture
11/28/00 10:04 AM ET
Biotech/Pharmaceuticals
Some Shying Away From Shire as New Hyperactivity Remedies Emerge
11/27/00 10:32 AM ET
Competition threatens the British drugmaker`s supremacy in a controversial market.
Mit 1,6 Mrd.$ müsste Millennium eigentlich in so einer
Korrekturphase mal auf Schnäppchenjagd gehen.
Das ist meiner Meinung nach ein günstiger Einstiegspunkt.
Vor allem in GB sind einige Firmen sehr günstig zu haben.
Johnny
Korrekturphase mal auf Schnäppchenjagd gehen.
Das ist meiner Meinung nach ein günstiger Einstiegspunkt.
Vor allem in GB sind einige Firmen sehr günstig zu haben.
Johnny
stefford
das heißt also strong buy oder
wie soll ich den Text vertehen????????
drKulka nervengeschädigt
das heißt also strong buy oder
wie soll ich den Text vertehen????????
drKulka nervengeschädigt
Doc Kulka,
Es gibt genügend Risiken in diesem Wert, die ihm gerade mal ein "Halten" zugestehen ! ..... nix "strong buy" !
Am 13./14.12.00 entscheidet es sich für MLNM/ILXO mit CAMPATH (gemeinsame Entwicklung), denn dann müssen die beiden Unternehmen vor die ODAC, wo dann über eine evtl. Zulassung von CAMPATH entschieden werden könnte.
Schnallt euch an !
SkyRocket
"Given that it is unknown what products the company might acquire and what their future revenue-generating potential might be, we believe that there is sufficient risk to justify a hold rating," said analyst Rob Toth in a recent note to investors.
Es gibt genügend Risiken in diesem Wert, die ihm gerade mal ein "Halten" zugestehen ! ..... nix "strong buy" !
Am 13./14.12.00 entscheidet es sich für MLNM/ILXO mit CAMPATH (gemeinsame Entwicklung), denn dann müssen die beiden Unternehmen vor die ODAC, wo dann über eine evtl. Zulassung von CAMPATH entschieden werden könnte.
Schnallt euch an !
SkyRocket
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