Novo Nordisk - Die ewig steigende Aktie (Seite 115)
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ISIN: DK0062498333 · WKN: A3EU6F · Symbol: NOV
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18.05.24 · wallstreetONLINE Redaktion |
17.05.24 · globenewswire  |
16.05.24 · Der Aktionär TV  |
Novo Nordisk A/S: Trading in Novo Nordisk shares by board members, executives and associated persons 15.05.24 · globenewswire |
Outperformance: Mit 4 Aktienfonds wie Warren Buffett die Benchmark schlagenWerte aus der Branche Pharmaindustrie
| Wertpapier | Kurs | Perf. % |
|---|---|---|
| 0,8000 | +45,45 | |
| 3,0000 | +42,18 | |
| 1,3000 | +30,00 | |
| 2,0600 | +24,85 | |
| 0,9600 | +18,93 |
| Wertpapier | Kurs | Perf. % |
|---|---|---|
| 20,360 | -11,48 | |
| 114,60 | -13,61 | |
| 1,1900 | -18,49 | |
| 23,700 | -19,52 | |
| 0,7800 | -29,73 |
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FOCUS-In diabetes war, Novo Nordisk aims to break mould with new pill
[Reuters]
ReutersFebruary 6, 2018
* Oral form of GLP-1 injection opens door to more patients
* Data from first of 10 Phase III trials due this quarter
* Semaglutide central to company's long-term growth profile
* Price and post-dose fasting key uncertainties for new pill
By Ben Hirschler
LONDON, Feb 6 (Reuters) - After nearly a century building a company worth $125 billion based on injectable drugs, Denmark's Novo Nordisk - the world's biggest insulin maker - wants to prove this year it can transform the diabetes market with a pill.
Novo's oral semaglutide medicine is important for ensuring the group's long-term growth - a critical mission after 2017 results last week revealed mounting price pressure in a crowded market targeting the world's 450 million diabetics.
Rivals, especially Eli Lilly, are watching Novo's final-stage oral semaglutide trials closely, ahead of the drug's potential 2020 launch.
The once-daily pill belongs to a blockbuster class of treatments known as GLP-1s that stimulate insulin production, the first of which were derived from the venomous bite of North America's Gila monster lizard. So far, all have been injections.
While diabetics with advanced disease need daily insulin shots, those at a less serious stage start on simple tablets, with GLP-1s added as a potent new option since 2005.
Today, GLP-1s are embraced as a highly effective diabetes therapy and semaglutide, which was approved as a once-weekly injection in December, has out-gunned rivals in efficacy. But the needle is still a barrier.
"There is resistance in some patients to move to an injectable medication," said Dr. Jason Gaglia, a diabetes expert at the Joslin Diabetes Center in Boston. "Once an oral is available I think there will be significant interest in it."
If the data stack up from 10 pivotal Phase III studies reporting results in 2018, the new drug could grab more than $5 billion in annual sales, Deutsche Bank analysts believe.
Others are more cautious but investors overall are betting oral and injectable semaglutide combined will supply around two-thirds of Novo's revenue growth over the next five years, according to Thomson Reuters consensus data.
That represents a life-line for Novo as it tries to differentiate itself in diabetes at a time when its smaller biopharma division is also struggling, prompting last month's abortive attempt to buy Belgian biotech Ablynx.
LATE BREAKFAST
But oral semaglutide is no simple tablet. This is a big, complex molecule, known as a peptide, which would normally be destroyed by stomach acid and it requires protection with a special compound to boost absorption.
What's more, the drug must be in close contact with the stomach wall, which means patients cannot eat for 30 minutes after taking it and the pill can also cause nausea, raising questions about its practicality.
Eli Lilly research chief Jan Lundberg told analysts last week: "It's really a sub-optimal oral agent."
That may be sour grapes by Novo's arch-rival, whose own work on developing an oral GLP-1 is only at the preclinical stage.
But making patients wait half an hour for breakfast could affect adherence and is a concern for investors - as is the question of what Novo will charge for a drug that may perform as well as a pricey injection but looks like rival pills that cost half as much.
Chief Science Officer Mads Krogsgaard Thomsen said Novo would pay close attention to such factors as it tries to reach the three-quarters of diabetics who are not yet on injections.
"If we get the balance between the drug's profile and the drug's price and market access right then we can do phenomenally well," he told Reuters.
Getting this far with oral GLP is already a notable achievement, especially after an earlier oral insulin project was abandoned as uneconomic in 2016.
Still, the devil will be in the details of the 10 Phase III trials, the first of which will deliver results this quarter. Key trials against Lilly and Boehringer Ingelheim's pill Jardiance and Merck & Co's Januvia will report later in 2018.
Most analysts expect oral semaglutide to beat these rivals in controlling both blood sugar and weight. The size of the benefit will feed into Novo's final pricing decision.
"The highest limit of where we could consider taking the pricing would be injectable GLP-1 and the lowest level would be somewhere in between current oral drugs and injectable GLP-1," Thomsen said.
[Reuters]
ReutersFebruary 6, 2018
* Oral form of GLP-1 injection opens door to more patients
* Data from first of 10 Phase III trials due this quarter
* Semaglutide central to company's long-term growth profile
* Price and post-dose fasting key uncertainties for new pill
By Ben Hirschler
LONDON, Feb 6 (Reuters) - After nearly a century building a company worth $125 billion based on injectable drugs, Denmark's Novo Nordisk - the world's biggest insulin maker - wants to prove this year it can transform the diabetes market with a pill.
Novo's oral semaglutide medicine is important for ensuring the group's long-term growth - a critical mission after 2017 results last week revealed mounting price pressure in a crowded market targeting the world's 450 million diabetics.
Rivals, especially Eli Lilly, are watching Novo's final-stage oral semaglutide trials closely, ahead of the drug's potential 2020 launch.
The once-daily pill belongs to a blockbuster class of treatments known as GLP-1s that stimulate insulin production, the first of which were derived from the venomous bite of North America's Gila monster lizard. So far, all have been injections.
While diabetics with advanced disease need daily insulin shots, those at a less serious stage start on simple tablets, with GLP-1s added as a potent new option since 2005.
Today, GLP-1s are embraced as a highly effective diabetes therapy and semaglutide, which was approved as a once-weekly injection in December, has out-gunned rivals in efficacy. But the needle is still a barrier.
"There is resistance in some patients to move to an injectable medication," said Dr. Jason Gaglia, a diabetes expert at the Joslin Diabetes Center in Boston. "Once an oral is available I think there will be significant interest in it."
If the data stack up from 10 pivotal Phase III studies reporting results in 2018, the new drug could grab more than $5 billion in annual sales, Deutsche Bank analysts believe.
Others are more cautious but investors overall are betting oral and injectable semaglutide combined will supply around two-thirds of Novo's revenue growth over the next five years, according to Thomson Reuters consensus data.
That represents a life-line for Novo as it tries to differentiate itself in diabetes at a time when its smaller biopharma division is also struggling, prompting last month's abortive attempt to buy Belgian biotech Ablynx.
LATE BREAKFAST
But oral semaglutide is no simple tablet. This is a big, complex molecule, known as a peptide, which would normally be destroyed by stomach acid and it requires protection with a special compound to boost absorption.
What's more, the drug must be in close contact with the stomach wall, which means patients cannot eat for 30 minutes after taking it and the pill can also cause nausea, raising questions about its practicality.
Eli Lilly research chief Jan Lundberg told analysts last week: "It's really a sub-optimal oral agent."
That may be sour grapes by Novo's arch-rival, whose own work on developing an oral GLP-1 is only at the preclinical stage.
But making patients wait half an hour for breakfast could affect adherence and is a concern for investors - as is the question of what Novo will charge for a drug that may perform as well as a pricey injection but looks like rival pills that cost half as much.
Chief Science Officer Mads Krogsgaard Thomsen said Novo would pay close attention to such factors as it tries to reach the three-quarters of diabetics who are not yet on injections.
"If we get the balance between the drug's profile and the drug's price and market access right then we can do phenomenally well," he told Reuters.
Getting this far with oral GLP is already a notable achievement, especially after an earlier oral insulin project was abandoned as uneconomic in 2016.
Still, the devil will be in the details of the 10 Phase III trials, the first of which will deliver results this quarter. Key trials against Lilly and Boehringer Ingelheim's pill Jardiance and Merck & Co's Januvia will report later in 2018.
Most analysts expect oral semaglutide to beat these rivals in controlling both blood sugar and weight. The size of the benefit will feed into Novo's final pricing decision.
"The highest limit of where we could consider taking the pricing would be injectable GLP-1 and the lowest level would be somewhere in between current oral drugs and injectable GLP-1," Thomsen said.
ROUNDUP: Novo Nordisk dämpft Erwartungen - Aktie knickt ein
13:39 Uhr 01.02.2018
http://www.boersennews.de/nachrichten/artikel/roundup--novo-…
...
Den Aktionären will Novo Nordisk gleichwohl die aktuelle Flaute mit einer leichten Dividendenanhebung versüßen: Sie sollen für das vergangene Jahr 7,85 Kronen je Aktie erhalten - das sind 3 Prozent mehr als im Vorjahr.
+
Katastrophe sieht anders aus!
Freundliche Grüße
supernova
13:39 Uhr 01.02.2018
http://www.boersennews.de/nachrichten/artikel/roundup--novo-…
...
Den Aktionären will Novo Nordisk gleichwohl die aktuelle Flaute mit einer leichten Dividendenanhebung versüßen: Sie sollen für das vergangene Jahr 7,85 Kronen je Aktie erhalten - das sind 3 Prozent mehr als im Vorjahr.
+
Katastrophe sieht anders aus!
Freundliche Grüße
supernova
also bitte... 7% im minus... hat novo was erwähnt, sie wollen jetzt in krypto oder cannabis machen? 
wo sind denn hier die konservativen anleger?
wo sind denn hier die konservativen anleger? Trading Spotlight
Antwort auf Beitrag Nr.: 56.894.885 von manfredpr am 01.02.18 08:51:30
Sicher kein Fehler !
Aber ein dicker Bock sich die Butter vom Brot nehmen zu lassen.
Kurzfristig nütz das jetzt aber nichts.
Zitat von manfredpr: Hab mir gleich mal ein paar gekauft.
Sicher kein Fehler !
Aber ein dicker Bock sich die Butter vom Brot nehmen zu lassen.
Kurzfristig nütz das jetzt aber nichts.
Antwort auf Beitrag Nr.: 56.895.068 von Taucher1975 am 01.02.18 09:09:03Guckst Du hier
http://www.deraktionaer.de/aktie/vertex-hui--novo-nordisk-pf…
http://www.deraktionaer.de/aktie/vertex-hui--novo-nordisk-pf…
Guten Tag,
ich bin seit ca. 5 Jahren Aktionär von Novo Nordisk und insgesamt nicht unerfahren, was Aktien angeht.
Gibt es Nachrichten von Belang, die derartige Kursschwankungen erklären können? Ich habe - bis auf den gescheiterten Übernahmeversuch - nichts gefunden. Die Aktie bewegt sich ja fast wie Bitcoin und Zockerinvests sind sicherlich nicht mein Spezialgebiet.
Viele Grüße
Ralf
ich bin seit ca. 5 Jahren Aktionär von Novo Nordisk und insgesamt nicht unerfahren, was Aktien angeht.
Gibt es Nachrichten von Belang, die derartige Kursschwankungen erklären können? Ich habe - bis auf den gescheiterten Übernahmeversuch - nichts gefunden. Die Aktie bewegt sich ja fast wie Bitcoin und Zockerinvests sind sicherlich nicht mein Spezialgebiet.
Viele Grüße
Ralf
Antwort auf Beitrag Nr.: 56.894.900 von schlauberker am 01.02.18 08:53:00
Warte besser noch etwas ab. Die Kurserholung sieht sehr gut aus 😄
Zitat von schlauberker: Ich hatte der Aktie eine zweite Chance gegeben. Aber nun ist tatsächlich Schluss.
Warte besser noch etwas ab. Die Kurserholung sieht sehr gut aus 😄
Antwort auf Beitrag Nr.: 56.894.618 von Herr Bö am 01.02.18 08:19:38
Jetzt ist Schluss
Ich hatte der Aktie eine zweite Chance gegeben. Aber nun ist tatsächlich Schluss. 
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